Dipyridamole CAS NO.58-32-2
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80017058
CAS NO.58-32-2
Purity 95+%
MDL NumberMFCD00010555
EINEC200-374-7
Molecular Formula C24H40N8O4
Molecular Weight 504.6256
| Aspect | Details |
|---|---|
| Definition | Dipyridamole is an antiplatelet agent and vasodilator used to reduce the risk of blood clots and improve blood flow. |
| Mechanism of Action | – Inhibits phosphodiesterase and adenosine deaminase, increasing intracellular cAMP and cGMP levels.<br>- Reduces platelet aggregation and promotes vasodilation. |
| Clinical Uses | – Prevents thromboembolic events in patients with mechanical heart valve replacements.<br>- Used in combination with warfarin for enhanced anticoagulation.<br>- Off-label use for stroke prevention.<br>- Used in pharmacologic stress testing for myocardial perfusion imaging. |
| Dosage Forms | – Oral tablets (25 mg, 50 mg, 75 mg).<br>- Intravenous solution (5 mg/mL) for stress testing. |
| Storage Conditions | Store at room temperature (68°F to 77°F or 20°C to 25°C), away from heat, moisture, and direct light. |
| Common Side Effects | – Chest pain, angina exacerbation, abnormal ECG.<br>- Headache, dizziness, flushing.<br>- Gastrointestinal disturbances (e.g., nausea, dyspepsia). |
| Contraindications | – Hypersensitivity to dipyridamole.<br>- Thrombocytopenia.<br>- Caution in patients with hypotension, unstable angina, or recent myocardial infarction. |
| Monitoring | – No routine laboratory monitoring required.<br>- Monitor for signs of hypoperfusion during stress testing. |
| Toxicity Management | Aminophylline can be used to reverse adverse effects during stress testing. |
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