Dipyridamole CAS NO.58-32-2

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Category:Active Pharmaceutical Ingredients   MOQ:100KG  Shipped directly from China

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Introduction

Catalog ID80017058

CAS NO.58-32-2

Purity 95+%

MDL NumberMFCD00010555

EINEC200-374-7

Molecular Formula C24H40N8O4

Molecular Weight 504.6256

Aspect Details
Definition Dipyridamole is an antiplatelet agent and vasodilator used to reduce the risk of blood clots and improve blood flow.
Mechanism of Action – Inhibits phosphodiesterase and adenosine deaminase, increasing intracellular cAMP and cGMP levels.<br>- Reduces platelet aggregation and promotes vasodilation.
Clinical Uses – Prevents thromboembolic events in patients with mechanical heart valve replacements.<br>- Used in combination with warfarin for enhanced anticoagulation.<br>- Off-label use for stroke prevention.<br>- Used in pharmacologic stress testing for myocardial perfusion imaging.
Dosage Forms – Oral tablets (25 mg, 50 mg, 75 mg).<br>- Intravenous solution (5 mg/mL) for stress testing.
Storage Conditions Store at room temperature (68°F to 77°F or 20°C to 25°C), away from heat, moisture, and direct light.
Common Side Effects – Chest pain, angina exacerbation, abnormal ECG.<br>- Headache, dizziness, flushing.<br>- Gastrointestinal disturbances (e.g., nausea, dyspepsia).
Contraindications – Hypersensitivity to dipyridamole.<br>- Thrombocytopenia.<br>- Caution in patients with hypotension, unstable angina, or recent myocardial infarction.
Monitoring – No routine laboratory monitoring required.<br>- Monitor for signs of hypoperfusion during stress testing.
Toxicity Management Aminophylline can be used to reverse adverse effects during stress testing.

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