Pharmaceutical Materials

Dioctyl sulfosuccinate sodium salt (DOSS), also known as Aerosol OT, is an anionic surfactant with the molecular formula C₂₀H₃₇NaO₇S and a molecular weight of 444.56 g/mol. It appears as a white waxy solid or colorless to pale yellow liquid, depending on formulation. DOSS is highly soluble in water (1.5 g/100 mL at 25°C) and organic solvents like benzene and tetrachloromethane, with a melting point of 173–179°C and a flash point of 91–95°C (open cup). Widely used in textiles, cosmetics, and pharmaceuticals, DOSS acts as an emulsifier, wetting agent, and detergent. Its applications extend to medicine as a laxative and softener for constipation relief. DOSS is also employed in electrophoresis for detecting estrogenic compounds and in membrane protein solubilization. Though stable under normal conditions, it decomposes in alkaline solutions and is incompatible with strong oxidizing agents.

Usage：

1.It is an excellent emulsifier, detergent and penetrant used in the textile industry. Good permeability and wettability.

2. Also called aerosol OT, used as a lubricant, can be used as a surfactant in the printing and dyeing industry and the cosmetics industry.

3. Surfactant, used as leveling agent in printing and dyeing industry, and also used as emulsion for photosensitive materials.

Packaging and Shipping： 25KG/drum.

Storage： Stored in a dry and ventilated warehouse; keep away from sunshine; avoid fire; avoid moisture.

Name	Dioctyl sulfosuccinate, sodium salt
Synonyms	AEROSOL OT Penetrant T AEROSOL OTB AEROSOL(R) OT AEROSOL(TM) OT Docusate sodium AEROSOL(R) OT-100 Dioctyl sodium sulfosuccinate Dioctylsulfosuccinate sodium salt DIETHYLHEXYL SODIUM SULFOSUCCINATE Sodium diethylhexyl sulfosuccinate Dioctyl sulfosuccinate, sodium salt 1,4-bis(2-ethylhexyl)sodiumsulfosuccinate Bis(2-ethylhexyl) sulfosuccinate sodium salt Sulfosuccinic acid, dioctyl ester, sodium salt
CAS	577-11-7
EINECS	209-406-4
InChI	InChI=1/C20H38O7S.Na/c1-5-9-11-16(7-3)14-26-19(21)13-18(28(23,24)25)20(22)27-15-17(8-4)12-10-6-2;/h16-18H,5-15H2,1-4H3,(H,23,24,25);/q;+1
InChIKey	APSBXTVYXVQYAB-UHFFFAOYSA-M

Molecular Formula	C20H37O7S.Na
Molar Mass	444.56
Density	1.1
Melting Point	173-179°C(lit.)
Boling Point	82.7°C
Water Solubility	1.5 g/100 mL (25 ºC)
Solubility	Soluble in water, ethanol, carbon tetrachloride, petroleum ether, xylene, acetone and vegetable oil, etc.
Vapor Presure	0Pa at 25℃
Appearance	White wax
Specific Gravity	1.005_PERCENT VOLATILE: 40
Color	White
Maximum wavelength(λmax)	[‘λ: 260 nm Amax: 0.1’, , ‘λ: 280 nm Amax: 0.05’]
Merck	14,3401
BRN	4117588
Storage Condition	Inert atmosphere,Room Temperature
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
Sensitive	Hygroscopic
MDL	MFCD00012455
Physical and Chemical Properties	Melting point 153-157°C water-soluble 1.5g/100 mL (25°C)
Use	Surfactant, dyeing and printing industry as leveling agent, can also be used as photosensitive material emulsion

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