Active Pharmaceutical Ingredients

Chemical Name: Diminazene aceturate

CAS No.: 908-54-3

Assay: ≥99.0%

Appearance: Yellow crystalline powder

DiMinazene aceturate More Details：

Specification:

Appearance Yellow crystalline powder

Purity 99.0% Min

Melting point 202 °C

Storage condition 0-6℃

DiMinazene aceturate Usage：

Veterinary medicine. For the treatment of pyrosomiasis and trypanosomiasis of large domestic animals

DiMinazene aceturate Packaging and Shipping：

25KG/drum

DiMinazene aceturate Storage：

Stored in a dry and ventilated warehouse; keep away from sunshine; avoid fire; avoid moisture.

Item	Content
Introduction	Diminazene Aceturate (CAS No.: 908-54-3) is an anti-trypanosomal agent used primarily in veterinary medicine to treat trypanosomiasis in livestock. It is also known for its anti-inflammatory properties and its ability to activate angiotensin-converting enzyme 2 (ACE2).
Chemical Information	– Molecular Formula: C₂₂H₂₉N₉O₆<br>- Molecular Weight: 515.52<br>- CAS Number: 908-54-3
Mechanism of Action	Diminazene Aceturate binds to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs, inhibiting DNA synthesis and replication in trypanosomes.
Medical Uses	– Veterinary Medicine: Used to treat trypanosomiasis (e.g., African sleeping sickness) in livestock.<br>- Research: Investigated for its anti-inflammatory properties and as an ACE2 activator.
Dosage Forms	– Powder: For veterinary use.<br>- Injection: Used in veterinary practice for treating infected animals.
Storage Conditions	Store at 4°C, sealed and protected from moisture. In solvent, store at -80°C for up to 2 years.
Solubility	– Water: 50 mg/mL (with sonication).<br>- DMSO: 25 mg/mL (with sonication; use fresh DMSO).
Applications	– Antiprotozoal Agent: Effective against Trypanosoma species.<br>- ACE2 Activator: Potential use in anti-inflammatory and cardiovascular research.
Safety Information	– Hazard Classifications: Flammable, toxic.<br>- Storage: Keep away from heat, sparks, and open flames.<br>- Handling: Use appropriate protective equipment.