Diminazene aceturate CAS No.:908-54-3
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Chemical Name: Diminazene aceturate
CAS No.: 908-54-3
Assay: ≥99.0%
Appearance: Yellow crystalline powder
DiMinazene aceturate More Details：
Specification:
Appearance Yellow crystalline powder
Purity 99.0% Min
Melting point 202 °C
Storage condition 0-6℃
DiMinazene aceturate Usage：
Veterinary medicine. For the treatment of pyrosomiasis and trypanosomiasis of large domestic animals
DiMinazene aceturate Packaging and Shipping：
25KG/drum
DiMinazene aceturate Storage：
Stored in a dry and ventilated warehouse; keep away from sunshine; avoid fire; avoid moisture.
| Item | Content |
|---|---|
| Introduction | Diminazene Aceturate (CAS No.: 908-54-3) is an anti-trypanosomal agent used primarily in veterinary medicine to treat trypanosomiasis in livestock. It is also known for its anti-inflammatory properties and its ability to activate angiotensin-converting enzyme 2 (ACE2). |
| Chemical Information | – Molecular Formula: C₂₂H₂₉N₉O₆<br>- Molecular Weight: 515.52<br>- CAS Number: 908-54-3 |
| Mechanism of Action | Diminazene Aceturate binds to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs, inhibiting DNA synthesis and replication in trypanosomes. |
| Medical Uses | – Veterinary Medicine: Used to treat trypanosomiasis (e.g., African sleeping sickness) in livestock.<br>- Research: Investigated for its anti-inflammatory properties and as an ACE2 activator. |
| Dosage Forms | – Powder: For veterinary use.<br>- Injection: Used in veterinary practice for treating infected animals. |
| Storage Conditions | Store at 4°C, sealed and protected from moisture. In solvent, store at -80°C for up to 2 years. |
| Solubility | – Water: 50 mg/mL (with sonication).<br>- DMSO: 25 mg/mL (with sonication; use fresh DMSO). |
| Applications | – Antiprotozoal Agent: Effective against Trypanosoma species.<br>- ACE2 Activator: Potential use in anti-inflammatory and cardiovascular research. |
| Safety Information | – Hazard Classifications: Flammable, toxic.<br>- Storage: Keep away from heat, sparks, and open flames.<br>- Handling: Use appropriate protective equipment. |
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