Difenoconazole 

CAS No.: 119446-68-3

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1. Chemical Identification

Property	Specification
IUPAC Name	1-((2-(2-Chloro-4-(4-chlorophenoxy)phenyl)-4-methyl-1,3-dioxolan-2-yl)methyl)-1H-1,2,4-triazole
Molecular Formula	C₁₉H₁₇Cl₂N₃O₃
Molecular Weight	406.3 g/mol
Synonyms	Bardos, Neu 1

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2. Chemical Classification

• Class: Dioxolane derivative
• Functional Groups:
  ✓ Aromatic ether
  ✓ Triazole
  ✓ Cyclic ketal
• Type: Conazole fungicide

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3. Biological Activity

Parameter	Characteristic
Target Enzyme	EC 1.14.13.70 (sterol 14α-demethylase)
Mode of Action	Inhibits ergosterol biosynthesis
Spectrum	Ascomycetes, Basidiomycetes, Deuteromycetes

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4. Applications

Target Crops:
✓ Winter wheat
✓ Oilseed rape
✓ Brassicas (cabbage, broccoli, cauliflower)

Controlled Pathogens:
✓ Septoria tritici
✓ Brown rust
✓ Light leaf spot
✓ Stem canker

Application Methods:
✓ Seed treatment
✓ Foliar spray
✓ Systemic fungicide

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5. Safety Profile

Toxicity:

• Moderate toxicity to:
  ✓ Humans
  ✓ Mammals
  ✓ Birds
  ✓ Aquatic organisms

Environmental Impact:

• Persistent environmental contaminant
• Classified as xenobiotic

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