Dichloroacetamide
Pharmaceutical Materials 2025-03-02
CAS Number: 683-72-7
Molecular Formula: C2H3Cl2NO
Molecular Weight: 127.96 g/mol
Appearance: White powder or crystals
Melting Point: 98-100 °C
Boiling Point: 234.3 °C at 760 mmHg
Density: 1.5 g/cm3
Usage: Used as an intermediate in medicine and pesticides.
| Aspect | Details |
|---|---|
| Name | Dichloroacetamide |
| CAS Number | 683-72-7 |
| Chemical Formula | C₂H₃Cl₂NO |
| Molecular Weight | 127.96 g/mol |
| Physical Appearance | White crystalline powder |
| Melting Point | 98–100°C (lit.) |
| Boiling Point | 233–234°C (745 mmHg) |
| Density | 1.5 g/cm³ (approx.) |
| Solubility | Soluble in hot water, alcohols, and ethers; sublimes with water vapor. |
| Reactivity | Acts as an organic synthesis intermediate; participates in amidation and cross-coupling reactions. |
| Applications | – Pharmaceuticals: Key intermediate in antineoplastic agent synthesis. |
| – Agrochemicals: Used in herbicide formulations (e.g., Dichlormid). | |
| – Materials Science: Precursor for polymers and functionalized molecules. | |
| Safety Information | – Hazards: Toxic (R43: Skin sensitization); causes eye and skin irritation. |
| – Handling: Wear PPE (gloves, goggles); avoid inhalation and ingestion. | |
| Storage Conditions | Store in a sealed container in a cool, dry place away from oxidizing agents and fire sources. |
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