Dibenzocyclooctyne (DBCO) modified dextran
Other Pharmaceutical 2025-03-04
CAS: N/A
Catalog: HY-164072
| Aspect | Details |
|---|---|
| Chemical Structure | – DBCO-Dextran is a polymer composed of dextran backbone modified with dibenzocyclooctyne (DBCO) groups.<br>- Dextran is a high molecular weight polysaccharide with excellent biocompatibility and biodegradability. |
| Mechanism of Action | – The DBCO groups enable click chemistry reactions with azide-containing molecules, forming stable covalent bonds.<br>- This bioorthogonal reaction occurs under mild conditions and is highly specific, making it suitable for complex biological environments. |
| Applications | – Drug Delivery: Used as a carrier for targeted drug delivery in cancer immunotherapy.<br>- Bioimaging: Facilitates the labeling and imaging of biological molecules.<br>- Material Science: Used in the development of functional materials like smart hydrogels and nanoparticles. |
| Storage Conditions | – Store at -20°C to maintain stability and activity.<br>- Avoid repeated freeze-thaw cycles. |
| Solubility | – Soluble in water and common organic solvents like DMSO. |
| Molecular Weight | – Commonly available in various molecular weights (e.g., 10k, 20k, 30k, 50k, 60k, 70k) for different applications. |
| Purity | – High purity products are available, typically >95%. |
| Supplier | – Available from suppliers like MedChemExpress and Xi’an QiYue Bio. |
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