Dexamethasone 21-acetate CAS NO.1177-87-3
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80017763
CAS NO.1177-87-3
Purity 98%
MDL NumberMFCD00027407
EINEC214-646-8
Molecular formula C24H31FO6
Molecular weight 434.4977
Melting point: 220~230°C
| Aspect | Details |
|---|---|
| Mechanism of Action | Dexamethasone 21-acetate is a corticosteroid that exerts its effects by binding to glucocorticoid receptors, regulating the body’s metabolism and immune response. It has potent anti-inflammatory properties. |
| Indications | – Inflammatory conditions such as dermatitis, psoriasis, and Stevens-Johnson syndrome.<br>- Autoimmune diseases like lupus and rheumatoid arthritis.<br>- Allergic conditions including asthma and allergies.<br>- Certain blood, kidney, and eye disorders. |
| Adverse Effects | – Common: Weight gain, fluid retention, increased blood pressure, elevated blood sugar, mood changes.<br>- Serious: Severe allergic reactions, adrenal insufficiency, increased risk of infections, reactivation of latent infections, Cushing’s syndrome, high blood sugar, vision problems, fluid retention, increased blood pressure, weakened bones, muscle problems, slowed growth in children, mood changes. |
| Storage Conditions | Store at room temperature (68°F to 77°F; 20°C to 25°C). Oral solutions should be discarded after 90 days of opening. |
| Special Considerations | – Long-term use may cause adrenal insufficiency and weakened bones.<br>- Monitor blood sugar levels, especially in diabetic patients.<br>- Regular eye exams are recommended to detect cataracts or glaucoma early |
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