DBCO-PEG4-NH2

Biomedicine 2025-03-04

CAS NO.: 1255942-08-5

Product purity: ≥95%

Molecular formula: C29H37N3O6

Molecular weight: 523.626

Product Usage: Applied to medical research, drug release, nanotechnology and new material research, cell culture. As well as in ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.

Basic Information of DBCO-PEG4-NH2

Item Description
Full Name Dibenzocyclooctyne-PEG4-Amine
CAS Number 1255942-08-5
Molecular Formula C29H37N3O6
Molecular Weight 523.62
Purity ≥95%
Appearance Solid/powder
Solubility Soluble in water, DMSO, DMF, and other organic solvents
Storage Conditions -20°C, dry, protected from light

Detailed Information of DBCO-PEG4-NH2

Item Description
Structure Consists of DBCO (dibenzocyclooctyne), PEG4 (polyethylene glycol with four ethylene oxide units), and an amine group (NH2) at the terminal end
Reactivity DBCO reacts with azides via strain-promoted azide-alkyne cycloaddition (SPAAC) for bioorthogonal labeling; the amine group can react with carboxylates, aldehydes, or other activated groups
Applications Bioconjugation, protein labeling, drug delivery, nanomaterial surface modification, and bioimaging
Advantages High reactivity, excellent biocompatibility, and water solubility

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