Creatine phosphate disodium salt tetrahydrate
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID 80071737
CAS NO.71519-72-7
Purity 98%
MDL NumberMFCD00150192
EINEC213-074-6
Molecular Formula C4H8N3O5P.2Na.4H2O
Molecular Weight 327.136
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Aspect
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Details
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Mechanism of Action
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In cells, it donates its phosphate group to ADP, regenerating ATP via the creatine kinase – catalyzed reaction. This process is crucial for rapid energy supply during short – term, high – intensity activities. For example, in muscle cells during a 100 – meter sprint, the pre – formed creatine phosphate can quickly replenish ATP levels, enabling continuous muscle contractions.
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Clinical Applications
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In cardiology, it is used to improve cardiac function post – myocardial infarction. By providing additional high – energy phosphates, it aids in the recovery of damaged heart muscle. In neurology, it shows potential in treating some neuromuscular disorders where energy metabolism is disrupted, like certain forms of muscular dystrophy, helping to enhance muscle function and reduce fatigue.
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Adverse Reactions
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Gastrointestinal issues such as nausea, diarrhea, and stomach discomfort are common with excessive intake. There are concerns about potential kidney stress, especially in those with pre – existing renal problems. High doses may increase the workload on kidneys as the body excretes excess creatine metabolites, which could potentially lead to impaired kidney function over time.
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Precautions
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People with kidney disease should use it under strict medical supervision. Diuretics can enhance its excretion, reducing its effectiveness. Pregnant and breastfeeding women should avoid it due to insufficient safety data. It’s also important to inform healthcare providers of all medications being taken, as there may be interactions with drugs affecting kidney function.
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