Coenzyme Q10 CAS 303-98-0
Nutritional Supplements 2025-03-11
COENZYME Q10
CAS No.: 303-98-0
Molecular Formula: C₅₉H₉₀O₄
Molecular Weight: 863.344 g/mol
1. DESCRIPTION
- Appearance: Yellow to orange crystalline powder
- Odor: Odorless
- Taste: Tasteless
- Stability: Degrades under light exposure
2. SPECIFICATIONS (USP40)
| Parameter | Standard Value |
|---|---|
| Identification | |
| A: IR | Matches reference spectrum |
| B: Color Reaction | Blue color appears |
| C: HPLC | Matches reference retention time |
| Melting Point | 48.0°C–52.0°C |
| Water Content | ≤0.2% |
| Residue on Ignition | ≤0.1% |
| Particle Size | ≥90% passes 80 mesh |
| Heavy Metals | ≤20 ppm |
| Residual Solvents | Complies with USP <467> |
| Chromatographic Purity | |
| – Coenzyme Q7, Q8, Q9, Q11 | ≤1.0% |
| – 2Z isomer & related impurities | ≤1.0% |
| – Total impurities | ≤1.5% |
| Microbial Limits | |
| – Total Plate Count | ≤1,000 CFU/g |
| – Yeast & Mold | ≤50 CFU/g |
| – Coliforms | ≤3 CFU/g |
| – E. coli | Negative/10g |
| – Salmonella | Negative/25g |
| – S. aureus | Negative/25g |
| Content (anhydrous basis) | 98.0%–101.0% (C₅₉H₉₀O₄) |
3. APPLICATIONS
- Cardiovascular: Adjunctive therapy for heart failure, arrhythmias, hypertension.
- Hepatology: Treatment for viral hepatitis, hepatic necrosis.
- Neurology: Management of cerebrovascular disorders.
- Oncology: Immune enhancement in cancer therapy.
- Antioxidant: Cellular protection against oxidative stress.
4. PACKAGING & STORAGE
- Packaging: 5 kg/drum × 2 drums/carton (or custom requirements).
- Storage:
- Airtight container, protected from light.
- Dry environment, temperature ≤25°C.
5. NOTES
- Handling: Avoid light exposure to prevent degradation.
- Regulatory: Complies with USP40 standards for pharmaceutical use.
