Cloxacillin sodium monohydrate
Active Pharmaceutical Ingredients 2025-03-03
English synonyms sodium (2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylate hydrate Catalog ID100360
CAS NO.7081-44-9
Purity95%
MDL NumberMFCD00150735
EINEC Molecular FormulaC19H17ClN3O5S.Na.H2O
Molecular Weight475.883
Appearance:Off-white solid
Boiling point:689.7°C at 760 mmHg
Flash point:370.9°C
| Category | Content |
|---|---|
| Generic Name | Cloxacillin Sodium Monohydrate |
| Chemical Formula | C19H17ClN3NaO5S |
| Mechanism of Action | Cloxacillin sodium monohydrate is a semisynthetic penicillin antibiotic that inhibits bacterial cell wall synthesis. It is resistant to β-lactamase enzymes, making it effective against β-lactamase-producing strains of Staphylococcus aureus. |
| Indications | Used for the treatment of infections caused by penicillinase-producing Staphylococcus aureus, such as pneumonia, endocarditis, and osteomyelitis. |
| Dosage Forms | Capsules, tablets, injection forms. |
| Side Effects | Common side effects include nausea, vomiting, diarrhea, and rash. Serious side effects may include allergic reactions, hepatitis, and Clostridium difficile-associated diarrhea. |
| Precautions | – Avoid use in patients with a history of penicillin allergy.<br>- Monitor for signs of allergic reactions or superinfections. |
| Developer | Originally developed by Beecham Pharmaceuticals (now GSK) |
| CAS Number | 7081-44-9 |
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