Clotrimazole CAS 23593-75-1
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Molecular Formula:C22H17ClN2
Molecular Weight: 344.8
CAS No.: 23593-75-1
Description
Clotrimazole is a white or pale yellow, crystalline powder. It is practically insoluble in water, soluble in ethanol (96 per cent) and in methylene chloride.
Application
Clotrimazole is mainly used for external use, and can treat skin mycosis, such as hand, foot and ankle, body lice, ear canal, vaginal mycosis. .
Packing and Storage
Preserve in tight, light-resistant containers.
Minimum Order
One package
| Item | Content |
|---|---|
| Introduction | Clotrimazole (CAS 23593-75-1) is an imidazole antifungal medication used to treat various fungal infections, including skin infections and oral candidiasis. |
| Mechanism of Action | Clotrimazole works by altering the permeability of the fungal cell wall, inhibiting fungal growth and killing the fungus. |
| Medical Uses | – Skin Infections: Athlete’s foot, jock itch, ringworm, and other fungal skin infections.<br>- Oral Candidiasis: Used as a lozenge for oropharyngeal candidiasis.<br>- Vaginal Candidiasis: Topical treatment for yeast infections. |
| Dosage Forms | – Topical Creams, Lotions, Solutions: Applied directly to the skin.<br>- Oral Lozenges: For oral fungal infections. |
| Common Side Effects | – Skin Reactions: Burning, stinging, redness, irritation, flaking.<br>- Allergic Reactions: Rash, itching, swelling, difficulty breathing. |
| Serious Side Effects | – Severe Allergic Reactions: Anaphylaxis, severe skin reactions.<br>- Localized Reactions: Blistering, oozing, open sores. |
| Precautions | – Avoid contact with eyes, nose, mouth, and vagina.<br>- Do not use on broken or irritated skin.<br>- Inform your doctor if you are pregnant, breastfeeding, or using other medications. |
| Storage Conditions | Store at room temperature, protect from moisture. |
| Chemical Information | – Molecular Formula: C₂₂H₁₇ClN₂<br>- Molecular Weight: 344.84.<br>- Purity: >98%.<br>- Melting Point: 143.0 to 147.0 °C.<br>- Solubility: Insoluble in water, soluble in methanol, ethanol, and dimethylformamide. |
| GHS Classification | – Signal Word: Warning<br>- Hazard Statements: H302, H315, H319, H413.<br>- Precautionary Statements: P270, P264, P280, P302+P352, P337+P313. |
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