Clorofene

Pharmaceutical Materials 2025-03-02

CAS Number: 120-32-1

Molecular Formula: C13H11ClO

Molecular Weight: 218.68 g/mol

Appearance: White to yellowish crystalline powder

Usage: Widely used as a broad-spectrum fungicide and antibacterial agent in hospitals, homes, and personal care products.

 

Aspect Details
Name Clorofene
Common Synonyms Chlorophene; 2.2′-Methylenebis(4-chlorophenol); Dichlorodiphenylmethane-4.4′-diol (misleading, but sometimes referenced in legacy contexts); Bis(4-chlorophenyl)methane-2.2′-diol (structurally inaccurate, simplified as common reference)
Correct Structural Clarification While the name “Clorofene” is colloquially used, its precise structure is often associated with 2.2′-methylenebis(4-chlorophenol), a bisphenol derivative with two 4-chlorophenol units linked by a methylene bridge.
CAS No. 120-32-1 (for 2.2′-Methylenebis(4-chlorophenol))
Molecular Formula C₁₃H₁₀Cl₂O₂
Molecular Weight 269.12 g/mol
Physical Properties
  • Appearance: White to off-white crystalline powder
  • Melting Point: 114-116 °C
  • Solubility: Poorly soluble in water; soluble in organic solvents like ethanol and acetone
Chemical Properties Acts as a potent antimicrobial agent due to its chlorinated phenolic structure, disrupting microbial cell membranes.
Applications
  • Used in disinfectants, antiseptics, and preservatives
  • Employed in personal care products (e.g., soaps, creams) and industrial cleaning agents
Safety Information
  • Handle with gloves and eye protection; avoid ingestion and inhalation
  • Store in a cool, dry place, away from strong oxidizers

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