Clopidogrel hydrogen sulfate
We are a manufacturer based in China, specializing in high-quality Clopidogrel hydrogen sulfate for industrial clients worldwide. Technical support and custom formulation available.
Category：Agrochemicals | Brand：MT
Factory Direct
7-30 Days Lead Time
MOQ: 100KG
Global Export
Introduction
Clopidogrel Hydrogen Sulfate (CAS No. 120202-66-6)
1. Basic Information
- IUPAC Name: Methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogen sulfate
- Molecular Formula: C₁₆H₁₆ClNO₂S·H₂SO₄
- Molecular Weight: 419.90 g/mol
- Appearance: White to off-white crystalline powder
- Optical Rotation: [α]²⁰D = +55° to +56° (c=2, methanol)
- Polymorphs: Form I (thermodynamically stable) and Form II
2. Physicochemical Properties
| Property | Specification |
|---|---|
| Melting Point | 184–188°C (Form I, dec.) |
| Solubility | – Water: ~50 mg/mL (25°C) |
| – Methanol: Freely soluble | |
| pKa | 4.5 (tertiary amine) |
| LogP (octanol/water) | 3.0 (free base) |
| Hygroscopicity | Slightly hygroscopic |
3. Pharmacopoeial Specifications
| Test | USP/EP Standard |
|---|---|
| Assay (HPLC) | 98.0–102.0% |
| Related Substances | ≤0.5% any individual impurity |
| Sulfate Content | 22.4–23.4% |
| Heavy Metals | ≤20 ppm |
4. Hazards (GHS Classification)
- Acute Toxicity: Oral LD₅₀ >2,000 mg/kg (rat)
- Reproductive Toxicity: Category 2 (H361d)
- Environmental Impact: Not classified
5. Storage & Handling
- Conditions: Tight containers, 15–30°C, protected from moisture
- Handling: Use PPE (gloves, mask) to avoid inhalation of dust
Disclaimer:
The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
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