Clopidogrel hydrogen sulfate
We are a manufacturer based in China. We specialize in providing high-quality Clopidogrel hydrogen sulfate for industrial clients across various sectors. Whether you need chemicals consultation or technical support, our team is here to help.
Category：Agrochemicals Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Clopidogrel Hydrogen Sulfate (CAS No. 120202-66-6)
1. Basic Information
- IUPAC Name: Methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogen sulfate
- Molecular Formula: C₁₆H₁₆ClNO₂S·H₂SO₄
- Molecular Weight: 419.90 g/mol
- Appearance: White to off-white crystalline powder
- Optical Rotation: [α]²⁰D = +55° to +56° (c=2, methanol)
- Polymorphs: Form I (thermodynamically stable) and Form II
2. Physicochemical Properties
| Property | Specification |
|---|---|
| Melting Point | 184–188°C (Form I, dec.) |
| Solubility | – Water: ~50 mg/mL (25°C) |
| – Methanol: Freely soluble | |
| pKa | 4.5 (tertiary amine) |
| LogP (octanol/water) | 3.0 (free base) |
| Hygroscopicity | Slightly hygroscopic |
3. Pharmacopoeial Specifications
| Test | USP/EP Standard |
|---|---|
| Assay (HPLC) | 98.0–102.0% |
| Related Substances | ≤0.5% any individual impurity |
| Sulfate Content | 22.4–23.4% |
| Heavy Metals | ≤20 ppm |
4. Hazards (GHS Classification)
- Acute Toxicity: Oral LD₅₀ >2,000 mg/kg (rat)
- Reproductive Toxicity: Category 2 (H361d)
- Environmental Impact: Not classified
5. Storage & Handling
- Conditions: Tight containers, 15–30°C, protected from moisture
- Handling: Use PPE (gloves, mask) to avoid inhalation of dust
Disclaimer:
The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
If you're ready to take the next step, Leave your message below and we’ll reply soon. 20+ years of chemical manufacturing & export experience, a partner you can trust.
Inquiry
Factory & Shipment
