Active Pharmaceutical Ingredients

Catalog ID80071733

CAS NO.41927-89-3

Purity 95+%

MDL NumberMFCD00149465

EINEC216-082-8

Molecular FormulaC20H21CaN7O7.5H2O

Molecular Weight601.5778

Melting point: >300°C

 

Category	Details
Chemical Name	Cinepazide Maleate
Other Names	Maleic Acid Guipaiqite, Clinau
Chemical Formula	C26H35N3O9
Molecular Weight	533.571 g/mol
CAS Number	26328-04-1
Appearance	White or grayish-white crystalline powder
Indications	Cerebrovascular diseases (e.g., cerebral arteriosclerosis, transient ischemic attacks) Cardiovascular diseases (e.g., coronary heart disease, angina pectoris) Peripheral vascular diseases (e.g., lower extremity arteriosclerosis obliterans)
Mechanism of Action	Blocks calcium channels in vascular smooth muscle cells Dilates cerebral, coronary, and peripheral blood vessels Enhances adenosine and cAMP effects, reduces oxygen consumption Improves red blood cell flexibility and deformability
Administration	Intravenous infusion as a diluted solution
Dosage	100 ml/h once daily in 500 ml of 10% glucose or saline
Side Effects	Gastrointestinal disturbances Neurological symptoms Skin reactions Abnormal liver and kidney function tests
Precautions	Use cautiously in patients with leukopenia Avoid in patients with incomplete hemostasis after intracranial bleeding Monitor for allergies Regular blood tests recommended
Storage Conditions	Store below -20°C, keep tightly closed, and protect from light

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