Chlorphenesin
Pharmaceutical Materials 2025-03-02
CAS Number: 104-29-0
Molecular Formula: C9H11ClO3
Molecular Weight: 202.63 g/mol
Appearance: White to off-white solid
Usage: Widely used as a preservative in cosmetics and has antifungal and antibacterial properties.
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| Property | Details |
|---|---|
| Molecular Formula | C9H11ClO3 |
| Molecular Weight | 202.63 g/mol |
| CAS Number | 104-29-0 |
| Appearance | White to off-white crystalline powder |
| Purity | Typically ≥98% |
| Melting Point | 77-79 °C |
| Boiling Point | 369.5 °C at 760 mmHg |
| Density | 1.3 ± 0.1 g/cm³ |
| Solubility | Soluble in organic solvents such as ethanol, DMSO; slightly soluble in water |
| Applications | Cosmetics, pharmaceuticals, and industrial applications |
| Safety Considerations | Handle with care; avoid contact with skin and eyes; store in a cool, dry place away from heat and moisture |
| Suppliers | Available from various chemical and cosmetic suppliers globally |
Applications
Chlorphenesin is a versatile compound with a wide range of applications in cosmetics, pharmaceuticals, and industrial sectors.
In cosmetics, Chlorphenesin is used as a preservative due to its broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as some fungi and yeasts. It is commonly found in products such as creams, lotions, shampoos, and makeup, where it helps to prevent microbial growth and extend product shelf life.
In pharmaceuticals, Chlorphenesin is used as an antiseptic and antifungal agent. It has been shown to be effective against a variety of pathogens, including those responsible for skin infections and vaginal yeast infections. It is also used as an immunosuppressant in certain medical formulations.
In industrial applications, Chlorphenesin is used as a solvent and intermediate in the synthesis of various organic compounds. Its unique chemical properties make it a valuable component in the production of dyes, resins, lubricants, and other chemicals.
Chlorphenesin is generally considered safe for use in cosmetics and pharmaceuticals when used within recommended concentrations. However, it is important to handle the compound with care and avoid contact with skin and eyes, as it may cause irritation. It should be stored in a cool, dry place away from heat and moisture to maintain its stability and efficacy.


