Chloromethyltrimethylsilane
Pharmaceutical Materials 2025-03-02
CAS Number: 2344-80-1
Molecular Formula: C4H11ClSi
Molecular Weight: 122.67 g/mol
Appearance: Colorless transparent liquid
Boiling Point: 88~89°C
Usage: Widely used in organic synthesis, as a crosslinking agent, and as a catalyst in chemical reactions.
| Attribute | Description |
|---|---|
| Chemical Name | Chloromethyltrimethylsilane |
| CAS Number | 1816-48-6 |
| Formula | (CH3)3SiCH2Cl |
| Molecular Weight | 121.69 g/mol |
| Synonyms | Chloromethyltrimethylsilyl chloride, Trimethyl(chloromethyl)silane |
| Appearance | Colorless to pale yellow liquid with a characteristic odor |
| Density | 0.89 g/mL at 25°C |
| Boiling Point | 62-64°C (1 mmHg) |
| Flash Point | -17°C (closed cup) |
| Solubility | Soluble in organic solvents such as ether, toluene, and hexane |
| Stability | Stable under normal conditions, but reacts with water and acids |
| Chemical Properties | Acts as a silylating agent in organic synthesis, protecting hydroxyl, carboxyl, and amino groups |
| Applications | Used in the preparation of silyl ethers, esters, and amides, as well as in the synthesis of drugs and other organic compounds |
| Safety Hazards | Flammable and may cause irritation to skin, eyes, and respiratory tract |
| Health Effects | Inhalation or ingestion may cause respiratory distress, nausea, and vomiting |
| Storage Conditions | Store in a cool, dry, well-ventilated area, away from incompatible materials, ignition sources, and moisture |
| Handling Precautions | Wear appropriate personal protective equipment and avoid contact with skin, eyes, and clothing. Use in a well-ventilated area. |
Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
