Chlorodimethylphenylsilane
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID92679
CAS NO.768-33-2
Purity 98%
MDL NumberMFCD00000499
EINEC212-193-0
Molecular FormulaC8H11ClSi
Molecular Weight170.711
Melting point<0°C”
| Category | Content |
|---|---|
| Name | Chlorodimethylphenylsilane (Phenyldimethylchlorosilane) |
| Chemical Formula | C8H11ClSi |
| CAS Number | 768-33-2 |
| Molecular Weight | 168.66 g/mol |
| Physical Properties | – Appearance: Clear colorless to light yellow liquid.<br>- Boiling point: 139°C.<br>- Density: 1.01 g/cm³.<br>- Solubility: Soluble in organic solvents like benzene, ether, and toluene. |
| Chemical Properties | – Reacts with water to produce hydrochloric acid.<br>- Sensitive to moisture. |
| Uses | – Used in the synthesis of enantioenriched allenylsilanes through an ortho-ester Claisen rearrangement.<br>- Used for nucleophilic silylation, alcohol derivatization, and enolate capture.<br>- Employed in Kumada-Fleming Tamao oxidation.<br>- Acts as a protecting group for alcohols and carboxylic acids in organic synthesis. |
| Storage | Store in a cool, dry place. Protect from moisture. |
| Safety | – Destructive to mucous membranes, upper respiratory tract, eyes, and skin.<br>- Toxic and moisture-sensitive. |
| Purification | Can be purified by fractional distillation through a packed column |
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