Fine chemical

This product is a colorless or yellowish liquid, which is highly irritating and decomposes in water. Freezing point -22.5 °c. Boiling Point 107 °c. The relative density was 1.4202. Refractive index 4530. Soluble in benzene, carbon tetrachloride, ether and chloroform.​

For the synthesis of medicines and pesticides, can also be used as extraction solvents, refrigerants, dyeing aids and lubricating oil additives.

​Name	Chloroacetyl chloride
Synonyms	CH2ClCOCl chloracetyl Chloracetyl Chloride Chloroacetyl chloride Acetylchloride,chloro- monochloroacetylchloridc alpha-Chloroacetyl chloride MONO CHLORO ACETYL CHLORIDE Chlorid kyseliny chloroctove chloruredechloracetyle(french)
CAS	79-04-9
EINECS	201-171-6

Physico-chemical Properties

Molecular Formula	C2H2Cl2O
Molar Mass	112.94
Density	1.419g/mLat 20°C
Melting Point	−22°C(lit.)
Boling Point	105-106°C(lit.)
Flash Point	>100°C
Water Solubility	reacts
Solubility	Miscible with ethyl ether, acetone, benzene and carbon tetrachloride.
Vapor Presure	60 mm Hg ( 41.5 °C)
Vapor Density	3.9 (vs air)
Appearance	Liquid
Color	Clear colorless to slightly yellow
Exposure Limit	ACGIH: TWA 0.05 ppm; STEL 0.15 ppm (Skin)NIOSH: IDLH 1.3 ppm; TWA 0.05 ppm(0.2 mg/m3)
Merck	14,2067
BRN	605439
Storage Condition	Store at RT.
Stability	Stable. Incompatible with strong bases, alcohols, strong oxidizing agents. May react violently on exposure to water or moisture.
Sensitive	Moisture Sensitive
Refractive Index	n20/D 1.453(lit.)
Physical and Chemical Properties	Characteristics of colorless or yellowish liquid, there is a strong irritation. melting point boiling point 107 ℃ freezing point -22.5 ℃ relative density 1.4202 refractive index 1.4530 solubility: soluble in benzene, carbon tetrachloride, ether and chloroform.
Use	Used in medicine, pesticide, can also be used as extraction solvent, refrigerant, dye aid and lubricating oil additives

Application

Chloroacetyl Chloride is an important intermediate of pesticide, which can produce insecticide dimethoate, omethoate, fungicide imazalil, metalaxyl, oxalachlor, herbicide alachlor, acetochlor, alachlor, butachlor, clachlor, trimethoprim, metolachlor, metolachlor, salbutamol, mefenozamide, etc, at the same time, it is also an important pharmaceutical intermediate, which can be used for the synthesis of chlordiazepoxide, diazepam, nitrazepam, lidocaine, praziquantel, mesocaine, thiazide, piperacillin, fluconazole, econazole and the like. It is used in the production of pesticide Dimethoate, fluoroacetamide, medicine, solvent, refrigerant, fire extinguishing agent, dyeing aid, lubricating oil additive, etc. Chloroacetyl Chloride is widely used, only herbicides have 3 series of more than 40 varieties need to consume Chloroacetyl Chloride. Chloroacetyl Chloride is a kind of active acylating agent and important organic synthesis intermediates, widely used in amino acids, pesticides, pharmaceuticals, dyes, additives, extraction solvents, refrigerants, fire extinguishing agents, lubricating oil additives, the synthesis of military toxic gases, especially in the most widely used pesticides, the amount is also the largest. It is an important intermediate for the synthesis of pesticide Oxadiazole, acetochlor, omethoate and so on. it can be used in organic synthesis, such as medicine, pesticide, extraction solvent, refrigerant, dyeing aid and lubricant additive. . Production of chloroacetophenone (tear gas), the preparation of amino acids.

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