Chlorhexidine hydrochloride
Pharmaceutical Materials 2025-03-02
CAS Number: 3697-42-5
Molecular Formula: C22H32Cl4N10
Molecular Weight: 578.37
Appearance: White crystalline powder
Usage: Widely used as an antiseptic and disinfectant due to its strong broad-spectrum bactericidal and bacteriostatic properties.
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| Property | Details |
|---|---|
| Chemical Name | Chlorhexidine hydrochloride |
| CAS Number | 3697-42-5 |
| Molecular Formula | C22H32Cl4N10·2HCl |
| Molecular Weight | 578.37 g/mol |
| Synonyms | Chlorhexidine dihydrochloride; 1.1′-Hexamethylenebis(5-(p-chlorophenyl)biguanide) dihydrochloride; 2.2′-hexane-1.6-diylbis(1-{amino[(4-chlorophenyl)amino]methylidene}guanidine) dihydrochloride, etc. |
| Appearance | White to off-white crystalline powder |
| Odor | Odorless |
| Density | 1.284 g/cm³ at 20°C |
| Melting Point | 255-262°C (some sources indicate 111-116°C) |
| Solubility | Sparingly soluble in water (0.06 g/100 mL at 20°C); very slightly soluble in ethanol (96%); soluble in propylene glycol |
| pH | N/A (depends on solution concentration) |
| Applications | Used as a broad-spectrum antiseptic and disinfectant with activity against both Gram-positive and Gram-negative bacteria, fungi, and some enveloped viruses. It is commonly used in medical products such as mouthwashes, surgical scrubs, and topical antiseptics. |
| Safety Information | May be irritating to eyes, respiratory system, and skin. Handle with appropriate personal protective equipment. Keep away from incompatible materials, heat, sparks, and open flames. Follow relevant safety regulations and instructions when using this chemical. |
