CeftazidiMe Dihydrochloride
Pharmaceutical Materials 2025-03-02
CAS Number: 73547-70-3.
Molecular Formula: C22H24Cl2N6O7S2.
Molecular Weight: 619.49796 g/mol.
Appearance: White or off-white powder.
Usage: Primarily used as a pharmaceutical intermediate for Ceftazidime.
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| Property | Details |
|---|---|
| Molecular Formula | C22H24Cl2N6O7S2 |
| Molecular Weight | 619.49 g/mol |
| CAS Number | 73547-70-3 |
| Appearance | White to off-white crystalline solid or powder |
| Purity | Typically ≥98% |
| Melting Point | N/A (decomposes before melting) |
| Boiling Point | N/A (decomposes before boiling) |
| Density | ~1.185 g/cm³ (predicted) |
| Solubility | Soluble in water and organic solvents such as DMSO |
| Applications | Antibacterial agent, pharmaceutical intermediate |
| Safety Considerations | Handle with care; avoid contact with skin and eyes; store in a cool, dry place away from moisture and strong acids |
| Suppliers | Available from various pharmaceutical and chemical suppliers globally |
Applications
Ceftazidime Dihydrochloride is a third-generation cephalosporin antibiotic widely used in the treatment of various bacterial infections. It exhibits broad-spectrum activity against both Gram-negative and some Gram-positive bacteria, making it an effective therapeutic option for a range of infections, including hospital-acquired pneumonia, complicated urinary tract infections, intra-abdominal infections, and sepsis.
As a pharmaceutical intermediate, Ceftazidime Dihydrochloride is utilized in the synthesis of cephalosporin-based antibiotics. Its high purity and stability make it a reliable starting material for the production of these important therapeutic agents.
Ceftazidime Dihydrochloride is typically administered via intravenous injection and is known for its efficacy against Pseudomonas aeruginosa, a common hospital-acquired pathogen. Its antibacterial activity is attributed to its ability to inhibit bacterial cell wall synthesis, leading to cell death.
Due to its potent antibacterial activity and favorable safety profile, Ceftazidime Dihydrochloride is a key component in the arsenal of antibiotics used to combat serious bacterial infections. Its availability from various global suppliers ensures its continued use in clinical settings and research applications.
