What is 2 5 dihydroxycinnamic acid methyl ester?
FAQ 2025-04-10 123
2,5-Dihydroxycinnamic acid methyl ester, also known as Methyl 2,5-dihydroxycinnamate, is a chemical compound with the molecular formula C₁₀H₁₀O₄ and a molecular weight of approximately 194.18 g/mol. It is a derivative of cinnamic acid, featuring a methyl ester group and two hydroxyl groups at the 2 and 5 positions of the phenyl ring. Properties Appearance: Typically exists as a yellow crystalline solid. Melting Point: Ranges from 178°C to 180°C.
What Is 2,2′-Azobis(2-methylpropionamidine) dihydrochloride CAS No.:2997-92-4 Used For?
FAQ 2025-04-10 112
2,2′-Azobis(2-methylpropionamidine) dihydrochloride (CAS No. 2997-92-4) is a chemical compound primarily used as a free radical initiator in polymerization reactions and biochemical research. Polymerization Initiator: Serves as an efficient initiator for the polymerization of acrylic, vinyl, and allylic monomers, enabling the synthesis of polymers with controlled molecular weights and structures. Particularly effective in aqueous solution
Why is cabazitaxel better than docetaxel?
FAQ 2025-04-10 139
Cabazitaxel is not universally “better” than docetaxel; rather, its superiority depends on specific clinical contexts, patient characteristics, and treatment histories. 1. Efficacy in Metastatic Castration-Resistant Prostate Cancer (mCRPC) Cabazitaxel: Second-Line Therapy: Approved for mCRPC after progression on docetaxel. Clinical trials (e.g., TROPIC) demonstrated improved overall survival (OS) and progression-free survival (PFS)
What type of chemotherapy is cabazitaxel?
FAQ 2025-04-10 139
Cabazitaxel is classified as a microtubule inhibitor and belongs to the taxane class of chemotherapy agents. Mechanism of Action: Cabazitaxel disrupts cell division by binding to tubulin, the protein subunit of microtubules. This binding stabilizes microtubules, preventing their depolymerization (breakdown) during mitosis. As a result, cancer cells are unable to complete cell division, leading to cell cycle arrest and apoptosis (programmed cell d
What are the side effects of amorolfine?
FAQ 2025-04-10 137
Side Effects of Amorolfine Amorolfine, available in topical formulations such as 5% nail lacquer and 0.25% cream, is generally well-tolerated, but minor side effects may occur, particularly with prolonged use or in sensitive individuals. Local Skin Reactions: Burning or Stinging Sensation: A transient burning or stinging feeling at the application site, often reported shortly after applying the nail lacquer. Itching: Mild to moderate itching, w
Which is better, amorolfine or terbinafine?
FAQ 2025-04-10 138
Comparative Evaluation of Amorolfine and Terbinafine: 1. Mechanism of Action: Amorolfine: Inhibits two key enzymes (Δ14-reductase and Δ8→Δ7-isomerase) in the ergosterol biosynthesis pathway of fungi, disrupting membrane integrity. Terbinafine: Non-competitively inhibits squalene epoxidase, causing accumulation of toxic squalene and depletion of ergosterol, essential for fungal cell membrane stability. 2. Efficacy: Amorolfine: Demonstrates broa
Antimicrobial Coatings as Pathogen Inhibitors in Food Packaging
Introduction Food safety remains a critical global concern, with foodborne pathogens causing millions of illnesses annually. Antimicrobial coatings have emerged as an innovative solution to inhibit microbial growth on food contact surfaces and packaging materials. These specialized coatings can extend shelf life while enhancing food safety by preventing contamination from bacteria, molds, and other harmful microorganisms. This article examines ho
What is3-(3-Hydroxyphenyl)propanoic Acid？
FAQ 2025-04-09 188
3-(3-Hydroxyphenyl)propanoic acid is an organic compound with the chemical formula C₉H₁₀O₃. It is also known by several synonyms, including 3-(3-Hydroxyphenyl)propionic acid, m-Hydroxyphenylpropionic acid, and 3-Hydroxyhydrocinnamic acid. Key Properties Appearance: Solid, typically in the form of a pale beige to light brown crystalline powder. Molecular Weight: 166.17 g/mol. Melting Point: Approximately 111°C. Solubility: Soluble in water, ethan
What is deazaflavin?
FAQ 2025-04-09 164
Deazaflavin is a structural analog of flavin cofactors, belonging to the field of organic chemistry. Its core characteristic is the substitution of one or more nitrogen atoms in natural flavin molecules (such as riboflavin or flavin mononucleotide, FMN) with carbon atoms. For example, 5-deazaflavin is a derivative where the N5 position in the flavin ring is replaced with a carbon atom (C5). Chemical Structure Molecular Formula: C₁₁H₇N₃O₂ (or C₁₁
What is the mechanism of action of DMAA?
FAQ 2025-04-09 143
DMAA (1,3-Dimethylamylamine) is a synthetic compound with a mechanism of action centered around its role as an indirect sympathomimetic amine. It functions primarily by stimulating the central nervous system (CNS) and triggering the release of neurotransmitters such as norepinephrine and dopamine. Here’s a detailed breakdown of its mechanism: Activation of the Sympathetic Nervous System: DMAA mimics the effects of endogenous catecholamine
what is 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid used for？
FAQ 2025-04-09 182
3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid (CAS No. 176969-34-9), also known as difluoropyrazole acid, is a versatile chemical intermediate widely used in the synthesis of pharmaceuticals, agrochemicals, and specialty materials. Its primary applications include: Pharmaceutical Intermediates: Serves as a key precursor for synthesizing antifungal agents, such as pyrazole-amide fungicides (e.g., fluxapyroxad, bixafen, and isopyrazam
what is 4-amino-6-chloro-1,3-benzenedisulfonamide used for?
FAQ 2025-04-09 124
4-amino-6-chloro-1,3-benzenedisulfonamide, also known as **dexamethasone-related naming confusion here is clarified as it’s actually a distinct compound (often referred to as 4-amino-6-chloro-1,3-benzene disulfonamide or chloraminophenamide in industry), is primarily utilized as a pharmaceutical intermediate. Key Applications Synthesis of Hydrochlorothiazide: It serves as a critical intermediate in the production of hydrochlorothiazide, a
