Capsaicin
Active Pharmaceutical Ingredients 2025-03-03
CAS Number: 404-86-4
Molecular Formula: C18H27NO3
Molecular Weight: 305.41 g/mol
Appearance: Colorless pungent crystalline compound
Usage: Primarily found in chili peppers, it is used as a food additive for its spicy taste, and also has applications in pharmaceuticals for its analgesic and anti-inflammatory properties.
| Category | Details |
|---|---|
| Chemical Name | Capsaicin |
| CAS Number | 404-86-4 |
| Molecular Formula | C18H27NO3 |
| Molecular Weight | 305.41 g/mol |
| Chemical Structure | Trans-8-methyl-N-vanillyl-6-nonenamide |
| Appearance | Colorless to pale yellow crystalline solid |
| Melting Point | 62-65°C |
| Boiling Point | Not applicable (decomposes before boiling) |
| Solubility | Soluble in organic solvents such as ethanol, ether, and chloroform; insoluble in water |
| Occurrence | Naturally occurring compound found in chili peppers (e.g., Capsicum annuum) |
| Biological Activity | Stimulates TRPV1 receptors in neurons, causing a sensation of heat or pain (pungency). Has anti-inflammatory, analgesic, and antioxidant properties. Can affect metabolism and potentially aid in weight loss. |
| Applications | Used as a food additive to provide spiciness in various dishes. Incorporated into topical creams and patches for pain relief. Utilized in self-defense sprays due to its ability to cause temporary blindness and pain. Studied for potential medical applications, including treatment of arthritis and neuropathic pain. |
| Safety Information | May cause skin and eye irritation. Handling should be done with appropriate personal protective equipment. Avoid ingestion and contact with mucous membranes. |
