Calcium levomefolate
Chemical Intermediates 2025-03-02
CAS No.: 151533-22-1 | Molecular Weight: 497.52 g/mol
1. Chemical Identification
| Property |
Specification |
| IUPAC Name |
Calcium (2S)-2-[[4-[[(2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino]benzoyl]amino]pentanedioate |
| Common Name |
Calcium L-methylfolate |
| Synonyms |
Metafolin®; (6S)-5-methyltetrahydrofolate calcium salt |
| Molecular Formula |
C₂₀H₂₃CaN₇O₆ |
| CAS No. |
151533-22-1 |
2. Physical & Chemical Properties
| Parameter |
Value |
| Appearance |
Off-white to yellowish crystalline solid |
| Purity (HPLC) |
≥99% |
| Solubility |
Slightly soluble in water (50-100 mg/mL at 20°C) |
| Storage |
2-8°C in airtight container, protect from light |
3. Production & Supply
| Parameter |
Detail |
| Annual Capacity |
200 metric tons |
| MOQ |
100g |
| Packaging |
100g (amber glass bottle), 1kg (double PE bag), 25kg (fiber drum) |
4. Quality Standards
| Test |
Specification |
| Purity (HPLC) |
≥99.0% |
| Water Content |
≤5.0% (KF) |
| Heavy Metals |
≤10 ppm |
| Optical Purity |
≥98% (6S isomer) |
| Microbiological |
Meets USP <61> |
5. Applications
- Pharmaceutical:
- Active folate form for dietary supplements
- Treatment of folate deficiency and MTHFR polymorphism
- Food Fortification:
- Added to infant formula and functional foods
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