Bromoacetyl bromide
We are a manufacturer based in China, specializing in high-quality Bromoacetyl bromide for industrial clients worldwide. Technical support and custom formulation available.
Category：Chemical Additives | Brand：MT
Factory Direct
7-30 Days Lead Time
MOQ: 100KG
Global Export
Introduction
Bromoacetyl Bromide
Chemical Formula: C₂H₂Br₂O
Structure: Acyl bromide with an acetyl group (-COCH₂-) where:
- A bromine atom is bonded to the carbonyl carbon.
- A bromo group (-Br) replaces one hydrogen on the adjacent methyl carbon.
Key Properties
- Physical State: Colorless to light yellow liquid with a pungent odor.
- Reactivity:
- Moisture-sensitive: Reacts violently with water, releasing hydrogen bromide (HBr).
- Highly reactive in acyl substitution reactions.
- Hazards: Corrosive, toxic, and flammable.
Applications
- Organic Synthesis:
- Introduces bromoacetyl groups into molecules for:
- Pharmaceuticals (e.g., drug intermediates).
- Agrochemicals (e.g., pesticide precursors).
- Fine chemicals and dye/polymer intermediates.
- Introduces bromoacetyl groups into molecules for:
- Peptide Synthesis:
- Activates carboxylic acids for peptide bond formation.
- Bond Formation:
- Facilitates carbon-carbon and carbon-heteroatom bond creation.
Safety Considerations ⚠️
- Handling:
- Use PPE (gloves, goggles, lab coat) and work in a fume hood.
- Avoid contact with skin, eyes, or inhalation.
- Storage:
- Keep in a cool, dry, airtight container away from moisture and incompatible substances (e.g., bases, oxidizers).
- Disposal: Follow hazardous waste protocols due to HBr release and toxicity.
Summary:
Bromoacetyl bromide’s high reactivity makes it indispensable for introducing bromoacetyl groups in chemical synthesis, but its corrosivity, toxicity, and moisture sensitivity demand stringent safety measures.
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