Bromhexine hydrochloride CAS No.611-75-6
Pharmaceutical Materials 2025-03-20
CAS No.611-75-6
Name
bromohexine hydrochloride
Synonyms
bisolvon
bromessina
BROMHEXINE HCL
bisolvonhydrochloride
BROMHEXINE HYDROCHLORIDE
bromohexine hydrochloride
2-amino-n-cyclohexyl-3.5-dibromo-n-methyl-benzylaminhydrochloride
2-amino-n-cyclohexyl-3.5-dibromo-n-methylbenzylaminehydrochloride
2-Amino-3.5-dibromo-N-cyclohexyl-N-methylbenzylamine hydrochloride
2-AMINO-3.5-DIBROMO-N-CYCLOHEXYL-N-METHYLBENZY-LAMINE HYDROCHLORIDE
N-(2-Amino-3.5-dibromobenzyl)-N-methylcyclohexylamine hydrochloride
n-(2-amino-3.5-dibromobenzyl)-n-methylcyclohexylamine hydrochloride
2.4-dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline hydrochloride
2-amino-3.5-dibromo-n-cyclohexyl-n-methyl-benzenemethanaminmonohydrochlo
| Attribute | Description |
|---|---|
| Chemical Name | Bromhexine Hydrochloride |
| CAS Number | 611-75-6 |
| Formula | C14H21Br2ClN2 |
| Molecular Weight | 412.59 g/mol |
| Synonyms | Bromhexine HCl, Bromhexine, Bromhexin, BISOLVON, Bisolvon HCl, etc. |
| Appearance | White or off-white crystalline powder |
| Solubility | Slightly soluble in water, more soluble in ethanol or chloroform, very soluble in hot ethanol |
| Melting Point | 240-244 °C |
| Boiling Point | 441.5 °C at 760 mmHg |
| pH | N/A (aqueous solutions may vary) |
| Indication | Used as an expectorant for the treatment of respiratory conditions such as acute and chronic bronchitis, asthma, bronchiectasis, and emphysema, especially in cases where the patient has difficulty expectorating viscid or tenacious mucus. |
| Mechanism of Action | It increases the secretion of bronchial mucosa, reduces the viscosity of mucus, and facilitates its expectoration by breaking down mucus polysaccharides and inhibiting the synthesis of glycoproteins in goblet cells and mucous glands. |
| Safety and Precautions | Should be used with caution in patients with peptic ulcer, liver or kidney disease. Pregnant and breastfeeding women should consult a physician before use. Keep out of reach of children. |
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