Boc-NH-PEG2-Tos CAS NO.: 206265-94-3

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Category:Biomedicine   MOQ:100KG  Shipped directly from China

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Introduction

CAS NO.: 206265-94-3

Product purity: ≥95%

Molecular formula: C18H29NO7S

Molecular weight: 403.49

Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as in ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.

Basic Information

Item Description
Full Name Boc-NH-PEG2-Tos (Tosyl-PEG2-NH-Boc)
CAS Number 192132-77-7
Molecular Formula C16H25NO6S
Molecular Weight 359.44
Purity ≥95%
Appearance White to off-white solid
Solubility Soluble in water, DMSO, DMF, DCM
Storage Conditions -20°C, dry, protected from light

Detailed Information

Item Description
Structure Contains a Boc-protected amine group, a PEG chain with two ethylene oxide units, and a tosylate (Tos) group
Reactivity – The Boc group can be deprotected under mild acidic conditions to form a free amine.<br>- The tosylate group is a good leaving group for nucleophilic substitution reactions
Applications – PROTAC Synthesis: Used as a linker in the synthesis of PROTACs (Proteolysis Targeting Chimeras) for selective protein degradation.<br>- Bioconjugation: Modifies proteins, peptides, and other biomolecules to improve stability and reduce immunogenicity.<br>- Drug Delivery: Enhances drug stability and targeting.<br>- Surface Modification: Improves biocompatibility of nanoparticles and other materials.
Advantages High biocompatibility, good water solubility, and versatile reactivity

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