
Bisbentiamine
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Category:Active Pharmaceutical Ingredients Own Brand:MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80020340
CAS NO.2667-89-2
Purity 96%
MDL NumberMFCD01726426
Molecular FormulaC38H42N8O6S2
Molecular Weight770.9201
Melting point: 140-145 °C
| Category | Information |
|---|---|
| Chemical Properties | – Molecular Formula: C₃₈H₄₂N₈O₆S₂<br>- Molecular Weight: 770.92 g/mol |
| Physical Properties | – Appearance: White to off-white powder<br>- Melting Point: 140-145°C<br>- Density: 1.38 g/cm³<br>- Solubility: Slightly soluble in DMSO and methanol |
| Mechanism of Action | – Bisbentiamine is a lipophilic derivative of thiamine (vitamin B1) that converts into thiamine upon administration.<br>- Enhances thiamine levels in the body, improving cellular energy production and acting as an antioxidant. |
| Clinical Uses | – Nutritional Supplement: Used to address thiamine deficiencies.<br>- Diabetic Neuropathy: Studied for its potential to mitigate nerve damage and improve symptoms.<br>- Cardiovascular Diseases: Investigated for its role in enhancing cardiac function and reducing oxidative stress.<br>- Neurological Disorders: Explored for its effects on oxidative stress and inflammation. |
| Administration | – Available in oral tablets, capsules, and injectable solutions.<br>- Typical dosages range from 150 to 300 mg per day, divided into two or three doses. |
| Side Effects | – Common: Nausea, bloating, diarrhea, headaches, dizziness, skin rashes.<br>- Rare: Allergic reactions (itching, swelling, severe dizziness, difficulty breathing). |
| Storage Conditions | Store in a hygroscopic environment, -20°C freezer, under inert atmosphere. |
| Synonyms | – Bisbentiamin<br>- Bisbentiamine disulfide<br>- Benzoylthiamine disulfide |
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