Bis-PEG1-C-PEG1-CH2COOH
Biomedicine 2025-03-04
CAS NO.: 2358775-67-2
Product purity: ≥95%
Molecular formula: C16H30O8
Molecular weight: 350.4
Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
Information of Bis-PEG1-C-PEG1-CH2COOH
| Item | Information |
|---|---|
| Chemical Name | Bis-PEG1-C-PEG1-CH2COOH |
| CAS Number | 2358775-67-2 |
| Molecular Formula | C₁₆H₃₀O₈ |
| Molecular Weight | 350.40 g/mol |
| Appearance | Off-white to yellow oil |
| Solubility | DMSO: 100 mg/mL (285.39 mM); ultrasonic recommended |
| Storage Conditions | Pure form: -20°C for 3 years, 4°C for 2 years;<br>In solvent: -80°C for 6 months, -20°C for 1 month |
| Application | Used as a PEG-based PROTAC linker for the synthesis of Proteolysis Targeting Chimeras (PROTACs) to selectively degrade target proteins.<br>Also used in drug delivery, bioconjugation, surface modification of nanoparticles, and polymer synthesis. |
| Synonyms | PROTAC Linker 26, 3,9,12,18-Tetraoxaicosane-1,20-dioic acid |
| Functional Groups | PEG1 units, central carbon linker, terminal carboxyl groups (-COOH) |
| Boiling Point | 521.6±50.0 °C (Predicted) |
| Density | 1.140±0.06 g/cm³ (Predicted) |
| pKa | 3.22±0.10 (Predicted) |
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