Benzocaine
Pharmaceutical Materials 2025-03-02
CAS Number: 94-09-7.
Molecular Formula: C9H11NO2.
Molecular Weight: 165.19 g/mol.
Appearance: White crystalline powder, odorless and tasteless.
Usage: It is used as a local anesthetic for skin and mucous membranes.
| Attribute | Details |
|---|---|
| Chemical Name | Benzocaine |
| CAS Number | 94-09-7 |
| Formula | C9H11NO2 |
| Molecular Weight | 169.19 g/mol |
| Synonyms | Ethyl p-aminobenzoate, Ethyl aminobenzoate, Anesthesin |
| Appearance | White crystalline powder |
| Solubility | Slightly soluble in water; soluble in alcohol, ether, and chloroform |
| Melting Point | 88-91°C |
| Boiling Point | 300°C (decomposes) |
| LogP | 2.16 (a measure of lipophilicity) |
| Pharmacological Properties | Local anesthetic; blocks nerve conduction by inhibiting the sodium ion influx required for the initiation and conduction of impulses |
| Applications | Used topically in products such as creams, gels, and ointments for relief of pain, itching, and discomfort associated with minor skin irritations, sunburn, insect bites, and sore throat |
| Route of Administration | Topical |
| Metabolism | Rapidly absorbed through the skin and metabolized in the liver; primarily excreted in the urine as conjugates |
| Side Effects | May include skin irritation, redness, burning, or itching; in rare cases, severe allergic reactions may occur |
| Contraindications | Should not be used in individuals with known hypersensitivity to benzocaine or any of its components; caution should be used in patients with impaired hepatic function |
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