Benserazide HCl
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80018042
CAS NO.14919-77-8
Purity 98%
MDL NumberMFCD00078571
Molecular Formula C10H15N3O5.HCl
Molecular Weight 293.7041
Melting point: 146~148℃
| Category | Details |
|---|---|
| Chemical Properties | Molecular formula: C10H16ClN3O5<br> Molecular weight: 286.7 |
| Physical Properties | Appearance: White to off-white crystalline solid<br> Melting point: 146°C<br> Solubility: Soluble in water (35.4 µg/mL at pH 7.4), dimethyl sulfoxide, and methanol; insoluble in ethanol and acetone |
| Mechanism of Action | Inhibits aromatic L-amino acid decarboxylase (AADC), preventing the conversion of L-DOPA to dopamine in the peripheral circulation. This increases the amount of L-DOPA reaching the central nervous system. |
| Therapeutic Uses | Parkinson’s Disease: Used in combination with L-DOPA to enhance its efficacy.<br> Cancer Therapy: Investigated as a cystathionine beta-synthase (CBS) inhibitor to enhance the effectiveness of chemotherapy drugs like paclitaxel. |
| Storage Conditions | Store at 2–8°C. |
| Safety Information | Light-sensitive; protect from light. |
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