Benserazide HCl

Active Pharmaceutical Ingredients 2025-03-03

Catalog ID80018042

CAS NO.14919-77-8

Purity 98%

MDL NumberMFCD00078571

Molecular Formula C10H15N3O5.HCl

Molecular Weight 293.7041

Melting point: 146~148℃

Category Details
Chemical Properties Molecular formula: C10H16ClN3O5<br> Molecular weight: 286.7
Physical Properties Appearance: White to off-white crystalline solid<br> Melting point: 146°C<br> Solubility: Soluble in water (35.4 µg/mL at pH 7.4), dimethyl sulfoxide, and methanol; insoluble in ethanol and acetone
Mechanism of Action Inhibits aromatic L-amino acid decarboxylase (AADC), preventing the conversion of L-DOPA to dopamine in the peripheral circulation. This increases the amount of L-DOPA reaching the central nervous system.
Therapeutic Uses Parkinson’s Disease: Used in combination with L-DOPA to enhance its efficacy.<br> Cancer Therapy: Investigated as a cystathionine beta-synthase (CBS) inhibitor to enhance the effectiveness of chemotherapy drugs like paclitaxel.
Storage Conditions Store at 2–8°C.
Safety Information Light-sensitive; protect from light.

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