Benfotiamine CAS 22457-89-2
Category：Vitamins
Introduction
Benfotiamine is pale-yellow or almost white powder; odorless. It is insoluble in water, methanol, ethanol, ether and chloroform, soluble in sodium hydroxide and sodium carbonate solution, slightly soluble in dilute hydrochloric acid solution.
Application
(1) Used for the prevention and treatment of vitamin B1 deficiency;
(2)Used for replenishment when the demand for vitamin B1 is increased and the intake is insufficient from food;
(3) Used for the treatment of non-alcoholic Wernicke encephalopathy;
(4) Used for the treatment of beriberi;
(5) Used for the treatment of the following diseases, it is presumed to be associated with vitamin B1 deficiency and metabolic disorders, such as: neuralgia; muscle pain, joint pain; peripheral neuritis, peripheral nerve palsy; myocardial metabolic disorder; constipation and other gastrointestinal motility obstacle.
Specification
| Appearance | Pale-yellow or almost white powder; odorless |
| Identification A | IR spectra shows the similarity between sample and standard |
| Identification B | The retention time of the major peak corresponds with it of the reference standard. |
| Solution color and clearness | Colorless to pale yellow clear solution |
| Chloride | NMT 0.053% |
| Sulfate | NMT 0.011% |
| Heavy metals | NMT 20ppm |
| Loss on drying | NMT l.5% |
| Related substance: | |
| Benzoic acid | NMT 0.1% |
| Thiamine | NMT 0.1% |
| Total impurities | NMT 1.0% |
| Purity | NLT 98.0% |
| Loss on Drying | Not more than 3.0 % |
| Residue on ignition (sulfated) | Not more than 0.20% |
| Assay | 98.5% to101.0% |
| PH | 5.5 to 7.0 |
Packing
25kg/drum or as customer’s requirements.
Storage
Preserve in well-closed containers. Stored in cool, dry and ventilated warehouse, and keep away from moisture.
