Barnidipine HCl
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80018936
CAS NO.104757-53-1
Purity 95+%
MDL NumberMFCD0015772
Molecular Formula C27H29N3O6.HCl
Molecular Weight 528.9966
| Category | Details |
|---|---|
| Chemical Properties | Molecular formula: C27H30ClN3O6<br> Molecular weight: 528.00 |
| Physical Properties | Appearance: White crystalline powder |
| Mechanism of Action | Barnidipine HCl is a lipophilic 1,4-dihydropyridine calcium antagonist that selectively blocks L-type calcium channels in vascular smooth muscle cells, reducing peripheral vascular resistance and lowering blood pressure. |
| Therapeutic Uses | Used for the treatment of mild to moderate essential hypertension, renal hypertension, and chronic stable angina. |
| Pharmacokinetics | Oral absorption is good, with onset of action within 1–1.6 hours. The drug reaches peak plasma concentration in 1–6 hours and has a half-life of approximately 10 hours. |
| Formulations | Available as capsules in 5 mg, 10 mg, and 15 mg strengths. |
| Dosage | Typical oral dosage is 5–15 mg once daily. |
| Safety and Side Effects | Common side effects include facial flushing, headache, palpitations, and mild hypotension. |
| Storage Conditions | Store in a cool, dry place, protected from light and moisture. |
| Synonyms | Mepirodipine hydrochloride, Hypoca |
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