Baloxavir marboxil
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
English synonyms (((R)-12-((S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-6,8-dioxo-3,4,6,8,12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl)oxy)methyl methyl carbonate Catalog ID100351
CAS NO.1985606-14-1
Purity 95%
MDL NumberMFCD31619272
EINEC Molecular Formula C27H23F2N3O7S
Molecular Weight 571.549
| Category | Content |
|---|---|
| Generic Name | Baloxavir Marboxil |
| Brand Name | Xofluza |
| Chemical Formula | C27H23F2N3O7S |
| Mechanism of Action | Baloxavir marboxil is a prodrug that is hydrolyzed to its active form, baloxavir. It inhibits the cap-dependent endonuclease activity of the viral RNA polymerase, preventing viral mRNA synthesis and viral replication. |
| Indications | – Treatment of influenza A and B virus infections in patients aged 5 years and older.<br>- Post-exposure prophylaxis for influenza in individuals aged 5 years and older. |
| Dosage Forms | Oral tablets (10 mg, 20 mg, 40 mg, 80 mg) |
| Administration | Single-dose oral administration. Dosing is based on patient age and weight. |
| Side Effects | Common side effects include headache, nausea, and diarrhea. |
| Developer | Shionogi & Co., Ltd. (Japan); marketed by Roche globally |
| Approval Date | – Approved in Japan on February 23, 2018.<br>- FDA approval on October 24, 2018. |
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