Arbidol HCl CAS NO.131707-23-8
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID 80017138
CAS NO.131707-23-8
Purity 98%
MDL NumberMFCD00344795
EINEC Molecular FormulaC22H25BrN2O3S.HCl
Molecular Weight513.881
| Aspect | Details |
|---|---|
| Mechanism of Action | Arbidol HCl is a broad-spectrum antiviral agent that inhibits viral entry and membrane fusion. It interferes with the attachment and internalization of viruses, including influenza A and B, by blocking the interaction between viral particles and host cell receptors. It also downregulates sialic acid-linked glycans on the cell surface, reducing viral entry. |
| Clinical Applications | It is used for the prevention and treatment of infections caused by influenza A and B viruses, acute viral respiratory infections, and severe acute respiratory syndrome (SARS). It can also be used to treat complications such as bronchitis and pneumonia. |
| Dosage Forms | Available as tablets. The typical dosage for adults is 200 mg three times daily for 5 days for treatment, and 100–200 mg once daily for prevention. |
| Side Effects | The incidence of adverse events is approximately 6.2%, with common side effects including nausea, diarrhea, dizziness, and elevated serum transaminase levels. |
| Contraindications | Contraindicated in individuals with a known allergy to the drug. Caution is advised in elderly patients over 65 years old, pregnant or breastfeeding women, and those with severe renal impairment or sinus node dysfunction. |
| Storage Conditions | Should be stored at -20°C. |
| Research and Development | Arbidol HCl has demonstrated antiviral activity against various viruses, including H5N1 influenza and SARS-CoV-2. It also has immunomodulatory properties, such as interferon induction and macrophage activation. |
| Special Considerations | The drug has shown good safety profiles in clinical trials and is suitable for widespread use in treating influenza and other viral infections. |
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