Anethole trithione
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80017958
CAS NO.532-11-6
Purity 98%
MDL NumberMFCD00129751
EINEC208-528-5
Molecular FormulaC10H8Os3
Molecular Weight 240.3649
Melting point: 111°C
| Category | Details |
|---|---|
| Chemical Properties | Molecular formula: C10H8OS3<br> Molecular weight: 240.31 g/mol<br> Appearance: Orange-red crystals<br> Melting point: 111°C<br> Solubility: Practically insoluble in water, slightly soluble in ethanol, soluble in pyridine, chloroform, benzene |
| Mechanism of Action | Stimulates salivary and bile secretion by acting on muscarinic receptors in the salivary and bile glands. Enhances liver glutathione levels and activities of glutathione-related enzymes, protecting hepatocytes from oxidative stress. |
| Therapeutic Uses | Dry Mouth (Xerostomia): Used to increase saliva production in conditions like Sjogren’s syndrome and radiation-induced xerostomia.<br> Liver Conditions: Used as an adjunctive therapy for cholecystitis, gallstones, indigestion, and acute/chronic hepatitis.<br> Potential Cancer Chemoprevention: Studied for its potential to inhibit tumorigenesis by increasing detoxification rates of carcinogens. |
| Dosage | Dry Mouth: Typically 25 mg three times daily.<br> Liver Conditions: Dosage varies based on the severity of the disease. |
| Side Effects | Generally well-tolerated, but may cause gastrointestinal disturbances. |
| Storage Conditions | Store in a cool, dry place, protected from light and moisture. |
| Safety Profile | Poisonous by intramuscular route; moderately toxic by ingestion and intraperitoneal routes |
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