Active Pharmaceutical Ingredients

Catalog ID80018002

CAS NO.68302-57-8

Purity 98%

MDL NumberMFCD00864790

EINEC Molecular Formula C16H14N2O4

Molecular Weight 298.2934

Melting point: >300°C

Category	Details
Chemical Properties	Molecular formula: C16H14N2O4<br> Molecular weight: 298.298 g/mol
Physical Properties	Appearance: White to yellowish-white powder<br> Melting point: Not specified<br> Solubility: Soluble in water
Mechanism of Action	Inhibits the release of inflammatory mediators such as histamine and leukotrienes. Acts as a leukotriene D4 antagonist and a phosphodiesterase inhibitor. Selectively inhibits TBK1 and IKK-ε, which are involved in inflammation and metabolic disorders.
Therapeutic Uses	Oral Ulcers: Used as a topical paste to treat recurrent aphthous ulcers (canker sores) and ulcers associated with Behçet disease.<br> Allergic Conditions: Used in Japan for bronchial asthma, allergic rhinitis, and conjunctivitis.<br> Metabolic Disorders: Investigated for its potential to improve insulin sensitivity and reduce inflammation in obese patients.
Formulations	Available as a 5% oral paste.
Storage Conditions	Store at room temperature, protect from light and moisture.
Safety Information	Side Effects: May cause a slightly painful stinging or burning sensation, nausea, or diarrhea.<br> Contraindications: Not recommended for patients with known allergies to amlexanox.<br> Pregnancy and Lactation: Use with caution; benefits should outweigh potential risks.

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