Active Pharmaceutical Ingredients

Catalog ID811963

CAS NO.1937-19-5

Purity 98%

MDL NumberMFCD00039074

EINEC217-707-7

Molecular FormulaCH6N4.HCl

Molecular Weight110.5461

Melting point: 162~166°C

Item	Information
Mechanism of Action	Aminoguanidine hydrochloride is a selective inhibitor of nitric oxide synthase (NOS) and diamine oxidase. It inhibits both constitutive and inducible NOS, reducing the production of nitric oxide, which is involved in various physiological and pathological processes.
Indications	It is used for the study of diabetes-related complications, such as diabetic nephropathy. It is also used in research on alveolar bone loss in periodontitis and as an antitussive agent.
Formulations	Available as a crystalline powder, commonly dissolved in DMSO for laboratory use.
Dosage	The dosage varies depending on the specific research application. For example, in animal studies, it is often administered at doses ranging from 10 to 100 mg/kg.
Side Effects	Potential side effects include gastrointestinal disturbances and hepatotoxicity at high doses.
Research Applications	It is widely used in research related to nitric oxide signaling pathways, inflammation, and bacterial infections.
Storage Conditions	Store in a cool, dry place, protected from moisture and light.
Chemical Properties	White to off-white crystals, with a molecular formula of CH7ClN4 and a molecular weight of approximately 110.55

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