Active Pharmaceutical Ingredients

Chemical Name: Allopurinol

CAS No.: 315-30-0

Assay: ≥ 99.0%

Appearance:White crystal

Allopurinol More Details：

Specification:

Appearance White crystal

Assay% 99%

molecular formula C5H4N4O

molecular weight 136.11

melting point 237-240 °C

Boiling point 295.67°C

Density 1.4295

Allopurinol Usage：

Allopurinol is used as pharmaceutical raw materials of gout suppressant , to cure the gout and gouty nephropathy.

Allopurinol Packaging and Shipping：

25kg/ drum，25kg/bag or as per buyer requirement.

Allopurinol Storage：

Store in a ventilated low-temperature dry warehouse;Store separately with oxidants, acids and alkali.

Item	Content
Introduction	Allopurinol (CAS No.: 315-30-0) is a xanthine oxidase inhibitor used primarily to treat gout, prevent tumor lysis syndrome, and manage hyperuricemia.
Chemical Properties	– Molecular Formula: C₅H₄N₄O<br>- Molecular Weight: 136.1
Mechanism of Action	Allopurinol is metabolized to oxypurinol, which inhibits xanthine oxidase, reducing the production of uric acid. This lowers serum and urinary uric acid levels, preventing gout flares and kidney stones.
Medical Uses	– Gout: Reduces uric acid levels to prevent gout attacks.<br>- Tumor Lysis Syndrome: Prevents hyperuricemia in cancer patients.<br>- Kidney Stones: Manages calcium and uric acid stones.
Dosage Forms	– Oral Tablets: 100 mg, 200 mg, 300 mg.<br>- Intravenous: Used for acute hyperuricemia.
Storage Conditions	Store at room temperature (20°C to 25°C), protect from moisture.
Side Effects	– Common: Nausea, headache, rash.<br>- Serious: Stevens-Johnson syndrome, toxic epidermal necrolysis.
Contraindications	– Hypersensitivity to allopurinol.<br>- Caution with kidney or liver disease.
Interactions	– Avoid with didanosine.<br>- Caution with azathioprine, cyclosporine, warfarin.