Allopurinol CAS 315-30-0
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Chemical Name: Allopurinol
CAS No.: 315-30-0
Assay: ≥ 99.0%
Appearance:White crystal
Allopurinol More Details：
Specification:
Appearance White crystal
Assay% 99%
molecular formula C5H4N4O
molecular weight 136.11
melting point 237-240 °C
Boiling point 295.67°C
Density 1.4295
Allopurinol Usage：
Allopurinol is used as pharmaceutical raw materials of gout suppressant , to cure the gout and gouty nephropathy.
Allopurinol Packaging and Shipping：
25kg/ drum，25kg/bag or as per buyer requirement.
Allopurinol Storage：
Store in a ventilated low-temperature dry warehouse;Store separately with oxidants, acids and alkali.
| Item | Content |
|---|---|
| Introduction | Allopurinol (CAS No.: 315-30-0) is a xanthine oxidase inhibitor used primarily to treat gout, prevent tumor lysis syndrome, and manage hyperuricemia. |
| Chemical Properties | – Molecular Formula: C₅H₄N₄O<br>- Molecular Weight: 136.1 |
| Mechanism of Action | Allopurinol is metabolized to oxypurinol, which inhibits xanthine oxidase, reducing the production of uric acid. This lowers serum and urinary uric acid levels, preventing gout flares and kidney stones. |
| Medical Uses | – Gout: Reduces uric acid levels to prevent gout attacks.<br>- Tumor Lysis Syndrome: Prevents hyperuricemia in cancer patients.<br>- Kidney Stones: Manages calcium and uric acid stones. |
| Dosage Forms | – Oral Tablets: 100 mg, 200 mg, 300 mg.<br>- Intravenous: Used for acute hyperuricemia. |
| Storage Conditions | Store at room temperature (20°C to 25°C), protect from moisture. |
| Side Effects | – Common: Nausea, headache, rash.<br>- Serious: Stevens-Johnson syndrome, toxic epidermal necrolysis. |
| Contraindications | – Hypersensitivity to allopurinol.<br>- Caution with kidney or liver disease. |
| Interactions | – Avoid with didanosine.<br>- Caution with azathioprine, cyclosporine, warfarin. |
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