
Alizapride HCl
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Category:Active Pharmaceutical Ingredients Own Brand:MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80071723
CAS NO.59338-87-3
Purity 98%
MDL NumberMFCD02183928
EINEC261-710-6
Molecular formula C16H21N5O2.HCl
Molecular weight 351.83118
| Item | Information |
|---|---|
| Mechanism of Action | Alizapride hydrochloride acts as a dopamine D2 receptor antagonist, primarily targeting the chemoreceptor trigger zone (CTZ) in the brain to suppress the vomiting reflex. It also enhances gastrointestinal motility by promoting acetylcholine release in the enteric nervous system. |
| Indications | It is used to treat nausea and vomiting of various causes, including postoperative nausea, chemotherapy-induced nausea, and vomiting associated with gastrointestinal disorders. |
| Formulations | Available as tablets for oral administration and as an injectable solution for intramuscular or intravenous use. |
| Dosage | The typical oral dosage ranges from 50 to 100 mg, taken two to three times daily. For injectable forms, the onset of action is faster, typically within 15 to 30 minutes. |
| Side Effects | Common side effects may include dizziness, headache, and gastrointestinal disturbances. In some cases, it may cause extrapyramidal symptoms at higher doses. |
| Storage Conditions | Store at 2-8°C, protected from light and moisture. |
| Research Applications | Alizapride hydrochloride is widely used in research related to gastrointestinal motility and antiemetic mechanisms. It is also studied for its potential in managing postoperative and chemotherapy-induced nausea. |
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