Albendazole oxide
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80020006
CAS NO.54029-12-8
Purity 98%
MDL NumberMFCD00797922EINEC
Molecular FormulaC12H15N3O3S
Molecular Weight 281.3308
Melting point: 226~228°C (dec)
| Category | Information |
|---|---|
| Chemical Properties | – Molecular Formula: C₁₂H₁₅N₃O₃S<br>- Molecular Weight: 281.33 g/mol |
| Physical Properties | – Appearance: White crystalline solid<br>- Melting Point: 226-228°C (decomposes) |
| Mechanism of Action | – Acts as a microtubule polymerization inhibitor, disrupting the formation of microtubules in parasitic worms.<br>- It is the active metabolite of albendazole, responsible for its anthelmintic activity. |
| Clinical Uses | – Used to treat a variety of parasitic infections, including those caused by roundworms, tapeworms, and flukes.<br>- Investigated for its potential as an antiparasitic agent in veterinary medicine. |
| Synthesis | – Can be synthesized by oxidizing albendazole with hydrogen peroxide in acetic acid. |
| Storage Conditions | – Store at -20°C for up to 3 years (powder); in solvent at -80°C for up to 1 year. |
| Solubility | – Soluble in DMSO (11 mg/mL); insoluble in water and ethanol. |
| Synonyms | – Ricobendazole<br>- Albendazole sulfoxide<br>- Albendazole S-oxide |
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