Adipoyl chloride
Pharmaceutical Materials 2025-03-02
CAS Number: 111-50-2
Molecular Formula: C6H8Cl2O2
Molecular Weight: 183.03 g/mol
Appearance: Colorless or reddish-brown liquid
Boiling Point: 105-107°C (2 mmHg)
Density: 1.259 g/cm³
Usage: Used as an intermediate in organic synthesis, particularly in the pharmaceutical industry.
| Category | Information |
|---|---|
| Basic Information | |
| Chemical Name | Adipoyl chloride |
| Other Names | Hexanedioyl dichloride, Adipic dichloride, 1.6-Dichlorohexane-1.6-dicarbonyl |
| CAS Number | 107-09-3 |
| Chemical Formula | C6H8Cl2O2 |
| Molecular Weight | 183.03 g/mol |
| Physical Properties | |
| Appearance | Colorless to pale yellow liquid with a pungent odor |
| Density | 1.235 g/mL at 25°C |
| Melting Point | 16-18°C |
| Boiling Point | 238°C |
| Flash Point | 110°C |
| Refractive Index | 1.465-1.467 |
| Solubility | Soluble in organic solvents such as toluene and ether, insoluble in water |
| Chemical Properties | |
| Functional Group | Acid chloride (-COCl) |
| Reactivity | Reacts with alcohols, amines, and other nucleophiles to form esters, amides, and other derivatives |
| Applications | |
| Industrial Uses | Used as an intermediate in the production of polyamides, polyurethanes, and other polymers. Also used in the synthesis of dyes, pharmaceuticals, and surfactants. |
| Safety Information | |
| Hazard Classification | Irritant, toxic, and flammable |
| Risk Phrases | R22 (Harmful if swallowed), R34 (Causes burns), R36/37/38 (Irritating to eyes, respiratory system, and skin) |
| Safety Phrases | S26 (In case of contact with eyes, rinse immediately with plenty of water and seek medical advice), S36/37/39 (Wear suitable protective clothing, gloves, and eye/face protection), S45 (In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)) |
| Storage Conditions | Store in a cool, dry, well-ventilated area away from heat, sparks, and ignition sources. Keep container tightly closed and separate from oxidants, acids, bases, and incompatible materials. |
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