Acetaminophen
Pharmaceutical Materials 2025-03-02
CAS Number: 103-90-2
Molecular Formula: C8H9NO2
Molecular Weight: 151.16 g/mol
Appearance: White crystalline powder
Usage: Primarily used as an antipyretic and analgesic to treat mild to moderate pain and fever.
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| Property | Details |
|---|---|
| Molecular Formula | C8H9NO2 |
| Molecular Weight | 151.16 g/mol |
| CAS Number | 103-90-2 |
| Appearance | White crystalline powder |
| Purity | Typically ≥98% (pharmaceutical grade) |
| Melting Point | 168-172 °C |
| Boiling Point | Decomposes before boiling |
| Density | ~1.26 g/cm³ |
| Solubility | Soluble in ethanol, DMSO; slightly soluble in water |
| Applications | Analgesic, antipyretic; used in pharmaceuticals |
| Safety Considerations | Use as directed; avoid overdose; keep out of reach of children; consult healthcare provider for long-term use |
| Suppliers | Widely available from pharmaceutical manufacturers and suppliers |
Applications
Acetaminophen, also known as paracetamol, is a widely used over-the-counter medication with analgesic (pain-relieving) and antipyretic (fever-reducing) properties. It is commonly used to relieve mild to moderate pain and reduce fever in adults and children.
In pharmaceuticals, Acetaminophen is a key ingredient in many formulations, including tablets, capsules, liquids, and suppositories. Its efficacy and safety profile make it a preferred choice for pain and fever management, particularly in patients who cannot tolerate non-steroidal anti-inflammatory drugs (NSAIDs) due to gastrointestinal issues or other contraindications.
Acetaminophen works by inhibiting the production of prostaglandins in the brain, which are chemicals that cause pain and fever. It is generally well-tolerated when used as directed, but overdose can lead to severe liver damage. Therefore, it is crucial to follow dosage instructions carefully and avoid combining it with alcohol or other medications containing Acetaminophen.
Its widespread availability and established safety record make Acetaminophen a staple in household medicine cabinets and healthcare settings worldwide.
