5-nitro-2-furfuraldehyde Diacetate CAS No. 92-55-7
Pharmaceutical Materials 2025-03-20
Product Name
5-nitro-2-furfuraldehyde Diacetate
5-Multiple Names
Nitro-2-Furfuraldehyde Diacetate;
(5-Nitro-2-Furanyl)-Methanediodiacetate(Ester);
2-Furanmethanediol,5-Nitro-,Diacetate;
5-Nitro-2-Furaldiacetate;
5-Nitro-2-Furancarboxaldehychemicalbookdediacetate;
5-Nitro-2-Furanmethandioldiacetate;
5-Nitro-2-Furanmethanediodiacetate;
5-Nitrofuraldehydediacetate;
5-Nitrofuraldehydediacetate
CAS No. 92-55-7
EC No. 202-166-1
MF No. C9H9NO7
MW No. 243.1703
It is used as a pharmaceutical intermediate for the preparation of furan anti-infective drugs such as Ritalin, furacilin, and furantadine.
Advantage of 5-nitro-2-furfuraldehyde Diacetate CAS No. 92-55-7
It is hygroscopic
Soluble in water and ethanol, soluble in ether
It turns pink when it meets iron, and decomposes into sulfuric acid and salicylic acid at high temperature
| Aspect | Details |
|---|---|
| Chemical Name | 5-Nitro-2-Furfuraldehyde Diacetate |
| Aliases | 5-Nitro-2-Furaldehyde Diacetate, 5-Nitrofurfural Diacetyl Acetal, 2-(Diacetoxymethyl)-5-Nitrofuran |
| CAS Number | 92-55-7 |
| EINECS Number | 202-166-1 |
| Molecular Formula | C₉H₉NO₇ |
| Molecular Weight | 243.17 g/mol |
| Physical State | White to off-white crystalline powder |
| Melting Point | 89-93°C |
| Boiling Point | 310.3°C at 760 mmHg |
| Density | 1.396 g/cm³ |
| Solubility | Insoluble in water; soluble in organic solvents like ethanol and DMSO |
| Applications | – Pharmaceutical Intermediates: Used in the synthesis of nitrofuran antibiotics such as Nitrofurantoin, Furazolidone, and Furacilin, which are effective against bacterial infections. – Chemical Synthesis: Acts as a versatile building block for the preparation of nitro-containing heterocycles and agrochemicals. |
| Safety Precautions | Classified as harmful (Xn, R68); may cause irreversible effects. Handle under fume hoods using appropriate PPE, and avoid inhalation, ingestion, and skin/eye contact. Store in sealed containers away from moisture and incompatible materials. |
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