Pharmaceutical Materials

5-Methyl-2-pyrazinecarboxylic acid (CAS No.: 5521-55-1), a pivotal heterocyclic compound, serves as a versatile intermediate in pharmaceuticals and agrochemicals. Its methyl, pyrazine, and carboxylic acid functional groups enable its integration into drug syntheses, notably as a key component in lipid-lowering agents like acipimox (Olbetam®) and the antidiabetic drug glipizide. Additionally, it finds applications in flavoring agents due to its unique taste profile. Beyond pharmaceuticals, research has explored its potential antimicrobial and antitumor properties, highlighting its therapeutic promise. Physically, it manifests as a light brown to orange crystalline powder, stable under ambient conditions but requiring careful handling due to its ocular toxicity (GHS H318). Its synthetic utility, coupled with ongoing investigations into its bioactivities, positions 5-Methyl-2-pyrazinecarboxylic acid as a valuable compound in both industrial and biomedical domains.

Usage: It is an important pharmaceutical intermediate.

Packaging and Shipping： 25kg/drum or as per buyer’s requirements.

Storage: Keep in dark place,Sealed in dry,Room Temperature.

 

Molecular Formula	C6H6N2O2
Molar Mass	138.12
Density	1.3471 (rough estimate)
Melting Point	167-171°C(lit.)
Boling Point	253.51°C (rough estimate)
Flash Point	145.2°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Presure	0.000172mmHg at 25°C
Appearance	Crystallization
Color	Orange
BRN	116005
pKa	3.53±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.5100 (estimate)
MDL	MFCD00068241
Physical and Chemical Properties	Appearance: pale yellow crystals melting point 166-169°C crystals. The melting point was 168-170 °c.
Use	It is an intermediate of glipizide and lezhiping An intermediate of the lipid-lowering drug amoxice.

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