5-Fluorosalicylic acid
Pharmaceutical Materials 2025-03-02
CAS Number: 345-16-4
Molecular Formula: C7H5FO3
Molecular Weight: 156.11
Appearance: White to off-white powder
Melting Point: 177-182°C
Boiling Point: 307.4°C at 760 mmHg
Flash Point: 139.7°C
Usage: Pharmaceutical intermediates, used in the synthesis of other organic compounds, pesticides, and in the preparation of certain coatings, plastics, and rubbers.
Names and Identifiers
| Name | 5-fluorosalicylic acid |
| Synonyms | RARECHEM AL BE 0856 5-fluorosalicylic acid 5-FLUOROSALICYLIC ACID 5-fluoro-2-hydroxybenzoic 5-fluoro-2-hydroxybenzoate 5-FLUORO-2-HYDROBENZOIC ACID 2-HYDROXY-5-FLUOROBENZOIC ACID 5-FLUORO-2-HYDROXYBENZOIC ACID 5-Fluoro-2-hydroxybenzoic acid 2-Hydroxy-5-Fluoro Benzoic Acid 1-chloro-4-fluoro-2-nitro-benzene 5-Fluoro-2-Hydroxy Benzoic Acid 5-Fluoro Sallicylic Acid 2-Hydroxy-5-Fluoro Benzoic Acid |
| CAS | 345-16-4 |
| EINECS | 206-455-3 |
| InChI | InChI=1/C6H3ClFNO2/c7-5-2-1-4(8)3-6(5)9(10)11/h1-3H |
345-16-4 – Physico-chemical Properties
| Molecular Formula | C7H5FO3 |
| Molar Mass | 156.11 |
| Density | 1.3290 (estimate) |
| Melting Point | 177-179 °C (lit.) |
| Boling Point | 307.4±27.0 °C(Predicted) |
| Flash Point | 98.5°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 0.0624mmHg at 25°C |
| Appearance | Bright yellow powder |
| Color | light brown |
| BRN | 2209120 |
| pKa | 2.68±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.554 |
| MDL | MFCD00002456 |
| Physical and Chemical Properties | White powder. Melting point 177-179 °c. |
345-16-4 – Risk and Safety
| Hazard Symbols | Xi – Irritant |
| Risk Codes | R36/37/38 – Irritating to eyes, respiratory system and skin. R37/38 – Irritating to respiratory system and skin. R36 – Irritating to the eyes |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 – Wear suitable protective clothing. S37/39 – Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| HS Code | 29182900 |
| Hazard Class | IRRITANT |
345-16-4 – Reference Information
| use | pharmaceutical intermediates. |
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