5-Chlorosalicylaldehyde CAS Number: 635-93-8
Pharmaceutical Materials 2025-03-02
Molecular Formula: C7H5ClO2
Molecular Weight: 156.57 g/mol
Appearance: White to slightly yellow crystalline powder
Melting Point: 99-103°C
Boiling Point: 228.8°C
Density: 1.404 g/cm³
Usage: It is used as an intermediate in the synthesis of pharmaceuticals, perfumes, and dyes.
5-Chlorosalicylaldehyde, also known as 2-hydroxy-5-chlorobenzaldehyde, is a versatile chemical compound with CAS number 635-93-8. It is primarily used as an intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical, fragrance, and dye industries. This compound features a combination of a hydroxyl group and an aldehyde group on a chlorinated benzene ring, contributing to its unique reactivity and applications.
| Property | Information |
|---|---|
| CAS Number | 635-93-8 |
| Physical Properties | |
| Appearance | White to slightly yellow crystalline powder |
| Melting Point | 100-102°C |
| Boiling Point | 228.8°C at 760 mmHg |
| Density | 1.4±0.1 g/cm³ |
| Flash Point | 92.2°C |
| Solubility | Soluble in alcohols, insoluble in water |
| Chemical Properties | |
| Molecular Formula | C7H5ClO2 |
| Molecular Weight | 156.56 g/mol |
| Functional Groups | Hydroxyl (-OH), Aldehyde (-CHO), Chlorine (-Cl) |
| pH (Aqueous Solution) | Not applicable (due to insolubility in water) |
| LogP | 2.57 (predicted) |
| Reactivity | Forms stable Schiff bases with amines, used as a protecting group in peptide synthesis |
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