5-Chlorosalicylaldehyde CAS Number: 635-93-8

Pharmaceutical Materials 2025-03-02

Molecular Formula: C7H5ClO2

Molecular Weight: 156.57 g/mol

Appearance: White to slightly yellow crystalline powder

Melting Point: 99-103°C

Boiling Point: 228.8°C

Density: 1.404 g/cm³

Usage: It is used as an intermediate in the synthesis of pharmaceuticals, perfumes, and dyes.

5-Chlorosalicylaldehyde, also known as 2-hydroxy-5-chlorobenzaldehyde, is a versatile chemical compound with CAS number 635-93-8. It is primarily used as an intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical, fragrance, and dye industries. This compound features a combination of a hydroxyl group and an aldehyde group on a chlorinated benzene ring, contributing to its unique reactivity and applications.

Property Information
CAS Number 635-93-8
Physical Properties
Appearance White to slightly yellow crystalline powder
Melting Point 100-102°C
Boiling Point 228.8°C at 760 mmHg
Density 1.4±0.1 g/cm³
Flash Point 92.2°C
Solubility Soluble in alcohols, insoluble in water
Chemical Properties
Molecular Formula C7H5ClO2
Molecular Weight 156.56 g/mol
Functional Groups Hydroxyl (-OH), Aldehyde (-CHO), Chlorine (-Cl)
pH (Aqueous Solution) Not applicable (due to insolubility in water)
LogP 2.57 (predicted)
Reactivity Forms stable Schiff bases with amines, used as a protecting group in peptide synthesis

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