5-Chloro-2-((R)-5-methyl-[1,4]diazepan-1-yl)benzoxazole hydrochloride Cas:1266664-66-7

Pharmaceutical Materials 2025-03-02

5-Chloro-2-((R)-5-methyl-[1,4]diazepan-1-yl)benzoxazole hydrochloride, with the CAS number 1266664-66-7, is a key intermediate in the synthesis of Suvorexant, a medication used to treat insomnia. This compound features a chlorinated benzoxazole ring attached to an (R)-5-methyl-[1,4]diazepane moiety, conferring unique pharmacological properties.

It is known for its high purity and stability, making it a valuable reagent in the pharmaceutical industry. Suvorexant, as a Schedule IV controlled substance in the United States, underscores the importance of this intermediate in the development of effective sleep aids.

Product Properties Details
CAS Number 1266664-66-7
Chemical Name 5-Chloro-2-((R)-5-methyl-[1,4]diazepan-1-yl)benzoxazole hydrochloride
Synonyms SUVOREXANT intermediate V, (R)-5-chloro-2-(5-methyl-[1,4]diazepan-1-yl)-benzoxazole hydrochloride
Molecular Formula C13H17Cl2N3O
Molecular Weight 302.19958 g/mol
Appearance White powder
Purity ≥98% – 99%
CAS Registry Number 1266664-66-7
Usage Pharmaceutical intermediate, specifically for the synthesis of Suvorexant

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