5-Chloro-2-((R)-5-methyl-[1,4]diazepan-1-yl)benzoxazole hydrochloride Cas:1266664-66-7
Pharmaceutical Materials 2025-03-02
5-Chloro-2-((R)-5-methyl-[1,4]diazepan-1-yl)benzoxazole hydrochloride, with the CAS number 1266664-66-7, is a key intermediate in the synthesis of Suvorexant, a medication used to treat insomnia. This compound features a chlorinated benzoxazole ring attached to an (R)-5-methyl-[1,4]diazepane moiety, conferring unique pharmacological properties.
It is known for its high purity and stability, making it a valuable reagent in the pharmaceutical industry. Suvorexant, as a Schedule IV controlled substance in the United States, underscores the importance of this intermediate in the development of effective sleep aids.
| Product Properties | Details |
|---|---|
| CAS Number | 1266664-66-7 |
| Chemical Name | 5-Chloro-2-((R)-5-methyl-[1,4]diazepan-1-yl)benzoxazole hydrochloride |
| Synonyms | SUVOREXANT intermediate V, (R)-5-chloro-2-(5-methyl-[1,4]diazepan-1-yl)-benzoxazole hydrochloride |
| Molecular Formula | C13H17Cl2N3O |
| Molecular Weight | 302.19958 g/mol |
| Appearance | White powder |
| Purity | ≥98% – 99% |
| CAS Registry Number | 1266664-66-7 |
| Usage | Pharmaceutical intermediate, specifically for the synthesis of Suvorexant |
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