5-Bromouracil CAS: 51-20-7

Chemical Intermediates 2025-03-02

CAS: 51-20-7

Appearance: White Powder

Purity: ≥99%

Capacity: 200mt/year MOQ: 216g

Application: Organic Intermediate

Standard: Enterprise export

Manufacturer: Jinan Finer Chemical Co., Ltd

Synonyms: 5-Bromo-2,4(1H,3H)-pyrimidinedione 5-Bromopyrimidine-2,4-diol

Molecular Formula: C4H3BrN2O2

Molecular Weight: 190.98

CAS Registry Number: 51-20-7

EINECS: 200-084-0

Melting point: 310 ºC

Water solubility: SOLUBLE IN COLD WATER

5-Bromouracil, with the CAS number 51-20-7, is a significant biochemical reagent primarily utilized in life science research. It is a pyrimidine derivative substituted with a bromine atom at the fifth position. This compound exhibits mutagenic activity, capable of inserting into DNA and altering base pair sequences by replacing thymine. Additionally, 5-bromouracil inhibits dihydrouracil dehydrogenase, making it a valuable tool in studying DNA replication and repair processes. Its unique chemical properties and biological activities contribute to its wide applications in scientific research.

Property Category Details
Chemical Name 5-Bromouracil
CAS Number 51-20-7
Physical Properties
Appearance White or off-white solid, crystalline powder
Melting Point Above 300°C (literature value)
Density Approximately 2.0±0.1 g/cm³
Solubility Soluble in water (50 mg/mL), also soluble in organic solvents like acetic acid and ethyl acetate
Chemical Properties
Molecular Formula C4H3BrN2O2
Molecular Weight 190.98 g/mol
Structural Formula Contains a pyrimidine ring with a bromine atom at the 5-position
pH (Aqueous Solution) Not specifically provided, but typically neutral
LogP (Octanol-Water Partition Coefficient) -0.35 (predicted)

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